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CAS No.: | 33755-46-3 |
---|---|
Name: | 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate |
Molecular Structure: | |
Formula: | C27H37 F O6 |
Molecular Weight: | 476.586 |
Synonyms: | Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 17-valerate (8CI); DV17; Dexamethasone 17-valerate; Dexamethasone valerate |
EINECS: | 251-669-2 |
Density: | 1.24 g/cm3 |
Boiling Point: | 607.5 °C at 760 mmHg |
Flash Point: | 321.2 °C |
Safety: | Poison by subcutaneous route. Moderately toxic by skin contact. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F−. |
PSA: | 100.90000 |
LogP: | 3.63680 |
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Product Name: Dexamethasone valerate (CAS NO.33755-46-3)
Molecular Formula: C27H37FO6
Molecular Weight: 476.5774832g/mol
Mol File: 33755-46-3.mol
Einecs: 251-669-2
Boiling point: 598.9 °C at 760 mmHg
Flash Point: 316 °C
Density: 1.24 g/cm3
Surface Tension: 50.8 dyne/cm
Enthalpy of Vaporization: 102.31 kJ/mol
Vapour Pressure: 7.72E-17 mmHg at 25
XLogP3: 3.6
H-Bond Donor: 2
H-Bond Acceptor: 7
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | oral | > 3gm/kg (3000mg/kg) | Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 8, Pg. 23, 1982. | |
mouse | LD50 | skin | 1784mg/kg (1784mg/kg) | Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 8, Pg. 23, 1982. | |
mouse | LD50 | subcutaneous | 238mg/kg (238mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS | Jitchuken Zenrinsho Kenkyuho. Central Institute for Experimental Animals, Research Reports. Vol. 8, Pg. 23, 1982. |
rabbit | LD50 | subcutaneous | 100mg/kg (100mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986. | |
rat | LD50 | oral | > 3gm/kg (3000mg/kg) | Drugs in Japan Vol. -, Pg. 662, 1990. | |
rat | LD50 | subcutaneous | 117mg/kg (117mg/kg) | Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 17, Pg. 1106, 1986. |
Poison by subcutaneous route. Moderately toxic by skin contact. Experimental reproductive effects. A steroid. When heated to decomposition it emits toxic fumes of F−.
Dexamethasone valerate ,its CAS NO. is 33755-46-3,the synonyms is 9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-valerate ; Dexamethasonevalerate ; DXMvalerate ; Dexamethasone-17-valerate ; DV 17 ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-[(1-oxopentyl)oxy]-, (11β,16α)- ; Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, 17-valerate (8CI) ; 9-Fluoro-11b,17,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione 17-valerate .