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Name |
VILOXAZINE |
EINECS | 256-281-7 |
CAS No. | 46817-91-8 | Density | 1.061 g/cm3 |
PSA | 39.72000 | LogP | 1.78130 |
Solubility | N/A | Melting Point |
185-186 ºC |
Formula | C13H19 N O3 | Boiling Point | 350.5 ºC at 760 mmHg |
Molecular Weight | 237.299 | Flash Point | 144.3 ºC |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also VILOXAZINE HYDROCHLORIDE. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
(?à)-2-(o-Ethoxyphenoxymethyl)morpholine;2-(2-Ethoxyphenoxymethyl)morpholine; Emovit; Viloxazin; Viloxazine |
Article Data | 8 |
Product Name: Viloxazine (CAS NO.46817-91-8)
Molecular Formula: C13H19NO3
Molecular Weight: 237.2949g/mol
Mol File: 46817-91-8.mol
Melting Point: 185-186 ºC
Boiling point: 350.5 °C at 760 mmHg
Flash Point: 144.3 °C
Density: 1.061 g/cm3
Surface Tension: 36.7 dyne/cm
Enthalpy of Vaporization: 59.51 kJ/mol
Vapour Pressure: 4.39E-05 mmHg at 25°C
XLogP3-AA: 1.5
H-Bond Donor: 1
H-Bond Acceptor: 4
Rotatable Bond Count: 5
Topological Polar Surface Area: 39.7
Heavy Atom Count: 17
Complexity: 213
Undefined Atom StereoCenter Count: 1
Covalently-Bonded Unit Count: 1
Viloxazine hydrochloride was approved for the treatment of clinical depression.Viloxazine has also been studied for the treatment of alcoholism, with some success.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 60mg/kg (60mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Handbook of Experimental Pharmacology. Vol. 55, Pg. 527, 1980. |
mouse | LD50 | oral | 552mg/kg (552mg/kg) | European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 27, Pg. 437, 1992. | |
rat | LD50 | intravenous | 60mg/kg (60mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Handbook of Experimental Pharmacology. Vol. 55, Pg. 527, 1980. |
rat | LD50 | oral | 2gm/kg (2000mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Handbook of Experimental Pharmacology. Vol. 55, Pg. 527, 1980. |
Poison by intravenous route. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx. See also VILOXAZINE HYDROCHLORIDE.
Viloxazine ,its CAS NO. is 46817-91-8,the synonyms is 2-[(2-Ethoxyphenoxy)methyl]morpholine ; 2-(2-Ethoxyphenoxymethyl)tetrahydro-1,4-oxazine ; Emovit ; Morpholine, 2-((2-ethoxyphenoxy)methyl)- .