2,6-Dichlorophenylhydrazine hydrochloride

Base Information

• Chemical Name: 2,6-Dichlorophenylhydrazine hydrochloride
• CAS No.: 50709-36-9
• Molecular Formula: C6H6Cl2N2^.HCl
• Molecular Weight: 213.494
• Hs Code.: 29280000
• European Community (EC) Number: 256-730-7
• UNII: MXU64S4WET
• DSSTox Substance ID: DTXSID50198764
• Mol file: 50709-36-9.mol

Synonyms:2,6-Dichlorophenylhydrazine hydrochloride;50709-36-9;(2,6-dichlorophenyl)hydrazine hydrochloride;1-(2,6-dichlorophenyl)hydrazine hydrochloride;(2,6-Dichlorophenyl)hydrazine monohydrochloride;Hydrazine, (2,6-dichlorophenyl)-, monohydrochloride;EINECS 256-730-7;MFCD00012930;(2,6-dichlorophenyl)hydrazine;hydrochloride;76195-83-0;2,6-DICHLOROPHENYLHYDRAZINE HCL;MXU64S4WET;SCHEMBL839849;DTXSID50198764;CQNIYLLTIOPFCJ-UHFFFAOYSA-N;(2,6-Dichlorophenyl)hydrazine HCl;AKOS005143658;CS-W014962;SB79176;2,6-dichlorophenylhydrazine-hydrochloride;AS-11559;BP-10840;SY009677;2,6-dichloro-phenylhydrazine hydrochloride;2,6-dichlorophenyl hydrazine hydrochloride;(2,6-dichlorophenyl)hydrazine.hydrochloride;1-(2,6-DICHLOROPHENYL)HYDRAZINE HCL;AM20060643;D2368;FT-0610625;2,6-Dichlorophenylhydrazine hydrochloride, 98%;EN300-109581;J-502918;Hydrazine, (2,6-dichlorophenyl)-, hydrochloride (1:?);Hydrazine, (2,6-dichlorophenyl)-, hydrochloride (1:1)

Chemical Property of 2,6-Dichlorophenylhydrazine hydrochloride

Chemical Property:

• Appearance/Colour: white to light yellow powder
• Melting Point: 225 °C (dec.)(lit.)
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 253.5 °C at 760 mmHg
• Flash Point: 107.1 °C
• PSA: 38.05000
• Density: 1.6100 (rough estimate)
• LogP: 3.85430
• Storage Temp.: Room temperature.
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 211.967481
• Heavy Atom Count: 11
• Complexity: 99.9

Purity/Quality:

99% ^*data from raw suppliers

2,6-Dichlorophenylhydrazine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T,Xi,Xn
• Statements: 20/21-25-36/37/38-20/21/22
• Safety Statements: 26-36/37/39-45-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)NN)Cl.Cl
• Uses: (2,6-Dichlorophenyl)hydrazine Hydrochloride 2,6-Dichlorophenylhydrazine hydrochloride was used in the preparation of 1-(2,6-dichlorophenyl)-4-methyl-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid, ethyl ester.

Technology Process of 2,6-Dichlorophenylhydrazine hydrochloride

There total 1 articles about 2,6-Dichlorophenylhydrazine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-Dichloroaniline (608-31-1) → (2,6-dichlorophenyl)hydrazine monohydrochloride (50709-36-9)

Guidance literature:

2,6-Dichloroaniline; With hydrogenchloride; sodium nitrite; In water; at -15 - 0 ℃; for 0.25h;

With hydrogenchloride; tin(ll) chloride; at -15 ℃; for 0.5h;

Reference yield: 100.0%

(2,6-dichlorophenyl)hydrazine monohydrochloride (50709-36-9) → (2,6-dichlorophenyl)hydrazine (14763-24-7)

Guidance literature:

With sodium hydroxide; water; sodium hydrogencarbonate;

Reference yield: 95.0%

4-propylbenzoyl chloride (52710-27-7) + (2,6-dichlorophenyl)hydrazine monohydrochloride (50709-36-9) → N'-(2,6-dichlorophenyl)-4-propylbenzohydrazide

Guidance literature:

(2,6-dichlorophenyl)hydrazine monohydrochloride; With triethylamine; In dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

4-propylbenzoyl chloride; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.5b01803

upstream raw materials:

2,6-Dichloroaniline

Downstream raw materials:

N-(2,6-Dichloro-phenyl)-N'-[2,2,2-trifluoro-1-phenyl-eth-(Z)-ylidene]-hydrazine

N-[Bis-(4-methoxy-phenyl)-methylene]-N'-(2,6-dichloro-phenyl)-hydrazine

4-{1-[(2,6-Dichloro-phenyl)-hydrazono]-ethyl}-benzonitrile

2-{1-[(2,6-Dichloro-phenyl)-hydrazono]-ethyl}-4,5-dimethyl-phenol

Refernces