R(+)-Gomisin M1

Base Information

• Chemical Name: R(+)-Gomisin M1
• CAS No.: 82467-50-3
• Molecular Formula: C₂₂H₂₆O₆
• Molecular Weight: 386.445
• DSSTox Substance ID: DTXSID601318545
• Wikidata: Q105191657
• Mol file: 82467-50-3.mol

Synonyms:R(+)-Gomisin M1;Gomisin M1;82467-50-3;Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxol-1-ol, 5,6,7,8-tetrahydro-2, 3,13-trimethoxy-6,7-dimethyl-, stereoisomer;(-)Gomisin L1;DTXSID601318545;HY-N1529;AKOS040762632;CS-0017078;B0005-188529;B0005-465628;B0005-465629;4,5,19-trimethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaen-3-ol

Chemical Property of R(+)-Gomisin M1

Chemical Property:

• Boiling Point: 568.6±50.0 °C(Predicted)
• PKA: 8.96±0.60(Predicted)
• PSA: 66.38000
• Density: 1.195±0.06 g/cm3(Predicted)
• LogP: 4.18450
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 386.17293854
• Heavy Atom Count: 28
• Complexity: 529

Purity/Quality:

98%min ^*data from raw suppliers

R(+)-GomisinM1 ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)O)OC)OCO3

Technology Process of R(+)-Gomisin M1

There total 1 articles about R(+)-Gomisin M1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H28O7 (82425-46-5) → (+/-)-gomisin M1 (82425-43-2,82467-50-3,95152-95-7,102681-52-7)

Guidance literature:

With potassium hydroxide; In ethanol; at 65 ℃; for 2h;

DOI:10.1248/cpb.30.132

Reference yield:

(+/-)-gomisin M1 (82425-43-2,82467-50-3,95152-95-7,102681-52-7) + dimethyl sulfate (77-78-1) → (+/-)-gomisin and (+/-)-γ-schizandrin (61281-37-6,66211-88-9,69176-52-9,82467-51-4,82467-52-5,82467-53-6,82467-54-7,64121-95-5)

Guidance literature:

With potassium carbonate; In acetone; at 45 ℃; for 3h;

DOI:10.1248/cpb.30.132

Reference yield:

(-)-gomisin L1 (82425-43-2,82467-50-3,95152-95-7,102681-52-7) + dimethyl sulfate (77-78-1) → gomisin N (61281-37-6,66211-88-9,69176-52-9,82467-51-4,82467-52-5,82467-53-6,82467-54-7,64121-95-5)

Guidance literature:

With potassium carbonate; In acetone; at 45 ℃; for 3h;

DOI:10.1248/cpb.30.132

upstream raw materials:

C₂₄H₂₈O₇

Downstream raw materials:

(+/-)-gomisin and (+/-)-γ-schizandrin

gomisin N

Refernces