10-Amino-1-decanol

Base Information

• Chemical Name: 10-Amino-1-decanol
• CAS No.: 23160-46-5
• Molecular Formula: C10H23NO
• Molecular Weight: 173.299
• Hs Code.: 2922199090
• European Community (EC) Number: 677-071-5
• DSSTox Substance ID: DTXSID20403579
• Nikkaji Number: J895.702I
• Wikidata: Q82207280
• Mol file: 23160-46-5.mol

Synonyms:10-Amino-1-decanol;10-aminodecan-1-ol;23160-46-5;1-Decanol, 10-amino-;MFCD02094313;1-Methyl-3-phenylpiperazine-d3;1189934-96-0;10- Aminodekanol-1;SCHEMBL197916;SCHEMBL1414980;DTXSID20403579;SWVSKCPPMNGBGL-UHFFFAOYSA-N;AKOS015855203;AB92448;CS-W017545;AS-57355;SY053876;FT-0661703;T70607;J-015015

Chemical Property of 10-Amino-1-decanol

Chemical Property:

• Appearance/Colour: White solid
• Vapor Pressure: 0.00101mmHg at 25°C
• Melting Point: 72 °C
• Refractive Index: 1.46
• Boiling Point: 268.8 °C at 760 mmHg
• PKA: 15.20±0.10(Predicted)
• Flash Point: 116.4 °C
• PSA: 46.25000
• Density: 0.889 g/cm³
• LogP: 2.75850
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 173.177964357
• Heavy Atom Count: 12
• Complexity: 76.2

Purity/Quality:

98% ^*data from raw suppliers

10-Amino-1-decanol ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCCCCO)CCCCN

Technology Process of 10-Amino-1-decanol

There total 2 articles about 10-Amino-1-decanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,10-Decanediol (112-47-0) → 10-amino-1-decanol (23160-46-5) + diaminodecane (646-25-3)

Guidance literature:

With ammonia; chlorocarbonylhydrido[4,5-bis(dicyclohexylphosphinomethyl)acridine]ruthenium(II); In toluene; at 155 ℃; for 12h; under 33228.3 Torr; Autoclave; Inert atmosphere;

Reference yield:

1,10-Decanediol (112-47-0) → 1,6-Hexanediamine (124-09-4) + 10-amino-1-decanol (23160-46-5)

Guidance literature:

With (carbonyl)(chloro)(hydrido)tris(triphenylphosphine)ruthenium(II); ammonia; [2-((diphenylphospino)methyl)-2-methyl-1,3-propanediyl]bis[diphenylphosphine]; In toluene; at 155 ℃; for 24h; under 29252.9 Torr; Autoclave; Inert atmosphere;

Reference yield: 91.0%

10-amino-1-decanol (23160-46-5) + benzyl chloroformate (501-53-1,94274-21-2) → O-benzyl-N-(10-hydroxydecyl) carbamate (96409-12-0)

Guidance literature:

With sodium carbonate; In dichloromethane; water; for 20h;

upstream raw materials:

1,10-Decanediol

Downstream raw materials:

4-Amino-salicylsaeure-(10-amino-decylester)

10-(tert-butoxycarbonylamino)decanyl benzoate

10-(benzoylamino)decanyl benzoate

C₃₀H₃₃F₃N₄O₃

Refernces

• 1、 -. "METHOD FOR PRODUCING ALKANOL AMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION". Paragraph 0088; 0103. . Retrieved 2016/10/27.
• 2、 -. "PROCESS FOR PREPARING DI-, TRI- AND POLYAMINES BY HOMOGENEOUSLY CATALYZED ALCOHOL AMINATION". Page/Page column 12; 16. . Retrieved 2012/09/22.