(4-methoxyphenyl)methanediyl diacetate

Base Information

• Chemical Name: (4-methoxyphenyl)methanediyl diacetate
• CAS No.: 14202-31-4
• Molecular Formula: C12H14O5
• Molecular Weight: 238.24
• Mol file: 14202-31-4.mol

Synonyms:

Chemical Property of (4-methoxyphenyl)methanediyl diacetate

Chemical Property:

• Vapor Pressure: 0.000182mmHg at 25°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-methoxyphenyl)methanediyl diacetate

There total 10 articles about (4-methoxyphenyl)methanediyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acetic anhydride (108-24-7) + 4-methoxy-benzaldehyde (123-11-5) → 4-methoxybenzaldehyde-1,1-diacetate (14202-31-4)

Guidance literature:

With Envirocat EPZG^R; at 60 - 65 ℃; for 3h;

Reference yield: 77.0%

p-Anisaldehyde dimethyl acetal (2186-92-7) + acetic anhydride (108-24-7) → 4-methoxybenzaldehyde-1,1-diacetate (14202-31-4) + 4-methoxy-benzaldehyde (123-11-5)

Guidance literature:

With titanium(IV) fluoride; at 20 ℃; for 65h; screw-capped vial; Inert atmosphere; neat (no solvent);

DOI:10.1055/s-0029-1218849

Reference yield: 75.0%

acetic anhydride (108-24-7) + 4-nitrobenzaldehdye (555-16-8) + 4-methoxy-benzaldehyde (123-11-5) → 4-methoxybenzaldehyde-1,1-diacetate (14202-31-4) + 4-nitrobenzylidene diacetate (2929-91-1)

Guidance literature:

With cobalt(II) bromide; at 20 ℃; for 0.5h; chemoselective reaction; Neat (no solvent);

DOI:10.1080/00397910902985499

upstream raw materials:

acetic anhydride

4-methoxy-benzaldehyde

p-methoxybenzal chloride

tetramethyl ammonium acetate

Downstream raw materials:

2,2,2-trichloro-1-(4-methoxyphenyl)ethan-1-ol

acetoxy-(4-methoxy-phenyl)-acetonitrile

2-(4-methoxyphenyl)-1,3-dithiane

5-(4-methoxyphenyl)-1,3-oxazole

Refernces

• 1、 Hajipour, Abdol R.,Zarei, Amin,Ruoho, Arnold E.. "P2O5/Al2O3 as an efficient heterogeneous catalyst for chemoselective synthesis of 1,1-diacetates under solvent-free conditions". . p. 2881 - 2884. Retrieved 2007.
• 2、 Curini, Massimo,Epifano, Francesco,Marcotullio, Maria Carla,Rosati, Ornelio,Nocchetti, Morena. "Preparation and deprotection of 1,1-diacetates (acylals) using zirconium sulfophenyl phosphonate as catalyst". . p. 2709 - 2711. Retrieved 2002.
• 3、 Bosco, J. W. John,Saikia, Anil K.. "Cerium(IV) triflate-catalyzed selective gem-diacetylation of aldehydes with acetic anhydride". . p. 77 - 84. Retrieved 2008.
• 4、 Koszelewski, Dominik,Ostaszewski, Ryszard. "The studies on chemoselective promiscuous activity of hydrolases on acylals transformations". . . Retrieved 2019/02/27.
• 5、 Sajjadifar, Sami,Nasri, Parastoo. "N-Propylsulfamic acid supported onto magnetic Fe3O4 nanoparticles (MNPs-PSA) as a green and reusable heterogeneous nanocatalyst for the chemoselective preparation and deprotection of acylals". . p. 6677 - 6689. Retrieved 2017/10/06.