LY2409881 trihydrochloride

Base Information

• Chemical Name: LY2409881 trihydrochloride
• CAS No.: 946518-60-1
• Molecular Formula: C₂₄H₂₉ClN₆OS*3ClH
• Molecular Weight: 594.436
• Mol file: 946518-60-1.mol

Synonyms:

Chemical Property of LY2409881 trihydrochloride

Chemical Property:

• Solubility.: ≥59.4 mg/mL in DMSO with ultrasonic; insoluble in EtOH; insoluble in H2O

Purity/Quality:

98% min ^*data from raw suppliers

2-[5-Chloro-2-[[3-(4-methylpiperazin-1-yl)propyl]amino]pyrimidin-4-yl]benzo[b]thiophene-4-carboxamideN-cyclopropylTrihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 2-[5-Chloro-2-[[3-(4-methylpiperazin-1-yl)propyl]amino]pyrimidin-4-yl]benzo[b]thiophene-4-carboxamide N-cyclopropyl Trihydrochloride is an inhibitor of IkB-kinase (IKK2). Small molecules that inhibits IkB-kinase and NF-κB pathways are potential anti-inflammatory drug candidate.

Technology Process of LY2409881 trihydrochloride

There total 2 articles about LY2409881 trihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

LY2409881 (946518-61-2) → 2-{5-chloro-2-[3-(4-methylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid cyclopropylamide trihydrochloride (946518-60-1)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane; for 0.05h;

Reference yield:

→ 2-{5-chloro-2-[3-(4-methylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid cyclopropylamide dihydrochloride (946518-60-1)

Guidance literature:

upstream raw materials:

LY2409881

Refernces