4-(6,8-dibromo-3,4-dihydroquinazolin-3-yl)cyclohexanol

Base Information

• Chemical Name: 4-(6,8-dibromo-3,4-dihydroquinazolin-3-yl)cyclohexanol
• CAS No.: 2088879-81-4
• Molecular Formula: C₁₄H₁₆Br₂N₂O
• Molecular Weight: 388.102
• Mol file: 2088879-81-4.mol

Synonyms:

Chemical Property of 4-(6,8-dibromo-3,4-dihydroquinazolin-3-yl)cyclohexanol

Chemical Property:

• Boiling Point: 506.2±60.0 °C(Predicted)
• Density: 1.84±0.1 g/cm3(Predicted)

Purity/Quality:

NLT 98% ^*data from raw suppliers

(1R,4R)-4-(6,8-dibromoquinazolin-3(4H)-yl)cyclohexan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (1R,4R)-4-(6,8-dibromoquinazolin-3(4H)-yl)cyclohexan-1-ol is an impurity of Ambroxol (A575900), a bronchosecretolytic drug and the metabolite of Bromhexine (B678600).

Technology Process of 4-(6,8-dibromo-3,4-dihydroquinazolin-3-yl)cyclohexanol

There total 1 articles about 4-(6,8-dibromo-3,4-dihydroquinazolin-3-yl)cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.2%

formic acid (64-18-6) + ambroxol hydrochloride (23828-92-4) → 4-(6,8-dibromo-3,4-dihydroquinazolin-3-yl)cyclohexanol (2088879-81-4)

Guidance literature:

at 80 - 90 ℃; Temperature;

upstream raw materials:

formic acid

ambroxol hydrochloride

Refernces