Furfuryl tetrahydropyranyladenine

Base Information

• Chemical Name: Furfuryl tetrahydropyranyladenine
• CAS No.: 109403-64-7
• Molecular Formula: C₁₅H₁₇N₅O₂
• Molecular Weight: 299.332
• UNII: FPU74MCG1O
• DSSTox Substance ID: DTXSID30911155
• Nikkaji Number: J1.351.825D
• Wikidata: Q27278124
• Mol file: 109403-64-7.mol

Synonyms:Furfuryl tetrahydropyranyladenine;109403-64-7;PRK-124;UNII-FPU74MCG1O;FPU74MCG1O;N-(furan-2-ylmethyl)-9-(oxan-2-yl)purin-6-amine;9H-Purin-6-amine, N-(2-furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-;Adenine, n6-furfuryl-9-(tetrahydropyran-2-yl)-;N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine;SCHEMBL2391367;DTXSID30911155;FURFURYL TETRAHYDROPYRANYLADENINE [INCI];6-furfurylamino-9-(tetrahydropyran-2-yl)-9h-purine;Q27278124;N-[(Furan-2-yl)methyl]-9-(oxan-2-yl)-9H-purin-6-amine

Chemical Property of Furfuryl tetrahydropyranyladenine

Chemical Property:

• Melting Point: 138-139℃
• Boiling Point: 526.4±60.0 °C(Predicted)
• PKA: 3.01±0.10(Predicted)
• Density: 1.47
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 299.13822480
• Heavy Atom Count: 22
• Complexity: 372

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCOC(C1)N2C=NC3=C(N=CN=C32)NCC4=CC=CO4

Technology Process of Furfuryl tetrahydropyranyladenine

There total 10 articles about Furfuryl tetrahydropyranyladenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3,4-dihydro-2H-pyran (110-87-2) + 6-furfurylaminopurine (525-79-1) → 6-furfurylamino-9-(tetrahydropyran-2-yl)-9H-purine (109403-64-7)

Guidance literature:

With formic acid; In ethyl acetate; at 78 ℃; for 3h;

DOI:10.1016/j.molstruc.2010.05.013

Reference yield: 78.9%

3,4-dihydro-2H-pyran (110-87-2) + kinetin (525-79-1) → 6-furfurylamino-9-(tetrahydropyran-2-yl)-9H-purine (109403-64-7)

Guidance literature:

With toluene-4-sulfonic acid; In various solvent(s); for 2h; Heating;

Reference yield: 71.0%

furan-2-ylmethanamine (617-89-0) + 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine (7306-68-5) → 6-furfurylamino-9-(tetrahydropyran-2-yl)-9H-purine (109403-64-7)

Guidance literature:

With triethylamine; In propan-1-ol; at 20 - 70 ℃; for 3h;

upstream raw materials:

3,4-dihydro-2H-pyran

kinetin

furan-2-ylmethanamine

6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine

Refernces

• 1、 Zahajská, Lenka,Nisler, Jaroslav,Voller, Ji?í,Gucky, Tomá?,Pospí?il, Tomá?,Spíchal, Luká?,Strnad, Miroslav. "Preparation, characterization and biological activity of C8-substituted cytokinins". . p. 115 - 127. Retrieved 2017.
• 2、 -. "6,9-Disubstituted Purine Derivatives And Their Use For Treating Skin". Page/Page column 8. . Retrieved 2008/06/13.