Dicyclohexylphenylphosphine

Base Information

• Chemical Name: Dicyclohexylphenylphosphine
• CAS No.: 6476-37-5
• Molecular Formula: C18H27 P
• Molecular Weight: 274.386
• Hs Code.: 2902909090
• European Community (EC) Number: 229-334-7
• DSSTox Substance ID: DTXSID0073372
• Nikkaji Number: J225.145K
• Wikidata: Q72468682
• Mol file: 6476-37-5.mol

Synonyms:Dicyclohexylphenylphosphine;Phenyldicyclohexylphosphine

Chemical Property of Dicyclohexylphenylphosphine

Chemical Property:

• Appearance/Colour: White to off-white crystalline powder
• Vapor Pressure: 5.43E-06mmHg at 25°C
• Melting Point: 60-61 ºC
• Boiling Point: 391.8 °C at 760 mmHg
• Flash Point: 201.1 °C
• PSA: 13.59000
• LogP: 5.45920
• Sensitive.: Air Sensitive
• Water Solubility.: Insoluble in water.
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 274.185037859
• Heavy Atom Count: 19
• Complexity: 226

Purity/Quality:

98% ^*data from raw suppliers

Dicyclohexylphenylphosphine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CCC(CC1)P(C2CCCCC2)C3=CC=CC=C3
• Uses: Dicyclohexylphenylphosphine ?is an organic phosphine compound, which can be used as a raw material for organic synthesis.

Technology Process of Dicyclohexylphenylphosphine

There total 19 articles about Dicyclohexylphenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

bromobenzene (108-86-1,52753-63-6) + dicyclohexylphosphane (829-84-5) → dicyclohexylphenylphosphine (6476-37-5)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); potassium hydroxide; In water; at 100 ℃; for 30h; Reagent/catalyst; Solvent; Inert atmosphere;

DOI:10.1055/s-0036-1590926

Reference yield:

triphenylphosphine (603-35-0) → dicyclohexylphenylphosphine (6476-37-5) + cyclohexyldiphenylphosphine (6372-42-5) + tricyclohexylphosphine (2622-14-2)

Guidance literature:

With n-butyllithium; hydrogen; bis(2,6-diisopropylphenoxy) trichloroniobium(V); In hexane; benzene; at 60 ℃; under 62057.8 Torr; Kinetics; var. of catalyst;

DOI:10.1039/c39950000849

Reference yield:

Dichlorophenylphosphine (644-97-3) + cyclohexylmagnesium bromide (931-50-0) → dicyclohexylphenylphosphine (6476-37-5)

Guidance literature:

In tetrahydrofuran;

DOI:10.1021/ja00530a008

upstream raw materials:

cyclohexyllithium

Dichlorophenylphosphine

chlorobenzene

lithium dicyclohexylphosphide

Downstream raw materials:

di(cyclohexyl)phenylphosphine oxide

dicyclohexylphenylphosphine selenide

dicyclohexyl(phenyl)phosphine sulfide

N,N-dimethyl-aniline

Refernces

• 1、 Chen, Xingyu,Wu, Hongyu,Yu, Rongrong,Zhu, Hong,Wang, Zhiqian. "Palladium-Catalyzed C-P(III) Bond Formation by Coupling ArBr/ArOTf with Acylphosphines". . p. 8987 - 8996. Retrieved 2021/06/30.
• 2、 Arockiam, Percia Beatrice,Lennert, Ulrich,Graf, Christina,Rothfelder, Robin,Scott, Daniel J.,Fischer, Tillmann G.,Zeitler, Kirsten,Wolf, Robert. "Versatile Visible-Light-Driven Synthesis of Asymmetrical Phosphines and Phosphonium Salts". supporting information. p. 16374 - 16382. Retrieved 2020/11/03.