13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid

Base Information

• Chemical Name: 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid
• CAS No.: 120591-53-9
• Molecular Formula: C₁₉H₂₂O₄
• Molecular Weight: 314.381
• Mol file: 120591-53-9.mol

Synonyms:

Chemical Property of 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid

There total 4 articles about 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oate (5335-63-7) → 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid (120591-53-9)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01632a026

Reference yield:

Methyl dehydroabietate (1235-74-1,1757-97-7,2756-34-5,7151-00-0,10178-27-5,10178-29-7,21699-55-8,24035-60-7) → 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid (120591-53-9)

Guidance literature:

Multi-step reaction with 3 steps

1: CrO₃

2: oxygen; dibenzoyl peroxide; FeSO₄

3: ethanolic KOH

With chromium(VI) oxide; potassium hydroxide; oxygen; iron(II) sulfate; dibenzoyl peroxide;

DOI:10.1021/ja01632a026

Reference yield:

methyl 7-oxodehydroabietate (17751-36-9) → 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oic acid (120591-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1: oxygen; dibenzoyl peroxide; FeSO₄

2: ethanolic KOH

With potassium hydroxide; oxygen; iron(II) sulfate; dibenzoyl peroxide;

DOI:10.1021/ja01632a026

upstream raw materials:

methyl 13-acetyl-7-oxo-8,11,13-podocarpatrien-18-oate

dehydroabietic acid

acetic anhydride

Methyl dehydroabietate

Downstream raw materials:

((1R,4aS,10aR)-7-Methoxy-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthren-1-yl)-diphenyl-methanol

Refernces

• 1、 Matsumoto,Imai,Sunaoka,Yoshinari. "The conversion of (+)-dehydroabietic acid into steroidal hormones". . p. 723 - 727. Retrieved 2007/10/02.