2'-(N-t-BOC-L-alanyl)taxol

Base Information

• Chemical Name: 2'-(N-t-BOC-L-alanyl)taxol
• CAS No.: 137234-34-5
• Molecular Formula: C₅₅H₆₄N₂O₁₇
• Molecular Weight: 1025.12
• Mol file: 137234-34-5.mol

Synonyms:

Chemical Property of 2'-(N-t-BOC-L-alanyl)taxol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2'-(N-t-BOC-L-alanyl)taxol

There total 1 articles about 2'-(N-t-BOC-L-alanyl)taxol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-N-Boc-Ala (15761-38-3) + taxol (33069-62-4) → 2'-(N-t-BOC-L-alanyl)taxol (137234-34-5)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1021/jm00079a019

Reference yield:

2'-(N-t-BOC-L-alanyl)taxol (137234-34-5) → 2'-ala-paclitaxel (131966-80-8)

Guidance literature:

With formic acid; for 0.5h;

DOI:10.1021/jm00079a019

upstream raw materials:

L-N-Boc-Ala

taxol

Downstream raw materials:

2'-ala-paclitaxel

Refernces