6β-methylandrost-4-ene-3,17-dione

Base Information

• Chemical Name: 6β-methylandrost-4-ene-3,17-dione
• CAS No.: 5696-36-6
• Molecular Formula: C₂₀H₂₈O₂
• Molecular Weight: 300.441
• Mol file: 5696-36-6.mol

Synonyms:

Chemical Property of 6β-methylandrost-4-ene-3,17-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6β-methylandrost-4-ene-3,17-dione

There total 5 articles about 6β-methylandrost-4-ene-3,17-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

exemestane (107868-30-4) → 6α-methylandrost-4-ene-3,17-dione (2241-94-3) + C20H30O2 + 6β-methylandrost-4-ene-3,17-dione (5696-36-6)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 5%-palladium/activated carbon; In ethanol; for 18h; stereoselective reaction; Reflux;

DOI:10.1039/c3ra41519h

Reference yield: 52.0%

6-methyleneandrosta-4-ene-3,17-dione (19457-55-7) → 6α-methylandrost-4-ene-3,17-dione (2241-94-3) + C20H30O2 + 6β-methylandrost-4-ene-3,17-dione (5696-36-6)

Guidance literature:

With diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 5%-palladium/activated carbon; In ethanol; for 18h; stereoselective reaction; Reflux;

DOI:10.1039/c3ra41519h

Reference yield:

→ 6α-Methyl-androsten-(4)-dion-(3,17) (2241-94-3,5696-36-6)

Guidance literature:

5α-Hydroxy-6β-methyl-androstandion-3,17, bas. Al2O3, 50 min, kochen;

DOI:10.1021/jo01063a634

upstream raw materials:

6-methyleneandrosta-4-ene-3,17-dione

exemestane

Downstream raw materials:

6α-methylandrost-4-ene-3,17-dione

Refernces