bis(m-bromophenyl)phosphinous acid

Base Information

• Chemical Name: bis(m-bromophenyl)phosphinous acid
• CAS No.: 108142-54-7
• Molecular Formula: C₁₂H₉Br₂OP
• Molecular Weight: 359.985
• Mol file: 108142-54-7.mol

Synonyms:

Chemical Property of bis(m-bromophenyl)phosphinous acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of bis(m-bromophenyl)phosphinous acid

There total 2 articles about bis(m-bromophenyl)phosphinous acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-dibromobenzene (108-36-1) → bis(m-bromophenyl)phosphinous acid (108142-54-7)

Guidance literature:

1,3-dibromobenzene; With magnesium; 1,1-dibromomethane; In tetrahydrofuran; for 1h; Reflux; Inert atmosphere;

With Diethyl phosphate; In tetrahydrofuran; at 0 ℃; Reflux;

DOI:10.1002/anie.201606637

Reference yield:

3-bromophenyl magnesium bromide (111762-31-3) + phosphonic acid diethyl ester (762-04-9) → bis(m-bromophenyl)phosphinous acid (108142-54-7)

Guidance literature:

In diethyl ether; for 0.5h; Heating;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + bis(m-bromophenyl)phosphinous acid (108142-54-7) → bis(m-bromophenyl)oxymethylphosphine oxide (108142-55-8)

Guidance literature:

upstream raw materials:

3-bromophenyl magnesium bromide

phosphonic acid diethyl ester

1,3-dibromobenzene

Downstream raw materials:

bis(m-bromophenyl)oxymethylphosphine oxide

Bis-m-bromophenylphosphinsaeurechlorid

bis(3-bromophenyl)phosphinic acid

Refernces

• 1、 Yarkevich, A. N.,Tkachenko, S. E.,Tsvetkov, E. N.. "NUCLEOPHILIC SUBSTITUTION OF CHLORINE ATOM IN DIARYL CHLOROMETHYLPHOSPHINE OXIDES". . p. 1430 - 1435. Retrieved 2007/10/02.