2-(2-Mercaptoethoxy)ethanol

Base Information

• Chemical Name: 2-(2-Mercaptoethoxy)ethanol
• CAS No.: 17643-17-3
• Molecular Formula: C4H10O2S
• Molecular Weight: 122.188
• European Community (EC) Number: 631-502-3
• DSSTox Substance ID: DTXSID801233799
• Nikkaji Number: J803.145B
• Mol file: 17643-17-3.mol

Synonyms:17643-17-3;2-(2-mercaptoethoxy)ethanol;2-(2-sulfanylethoxy)ethanol;Ethanol, 2-(2-mercaptoethoxy)-;2-mercaptoethoxyethanol;SCHEMBL61549;2-(2-mercaptoethoxy)-ethanol;2-(2-sulfanylethoxy)ethan-1-ol;CAULSPKRQNHKIT-UHFFFAOYSA-N;Thiol-PEG-OH, MW 1,000;Thiol-PEG-OH, MW 2,000;Thiol-PEG-OH, MW 3,400;Thiol-PEG-OH, MW 5,000;DTXSID801233799;Thiol-PEG-OH, MW 10,000;AKOS015897602;BP-26061;BP-26062;BP-26063;BP-26064;BP-26065;FT-0657892;A812182;51987-25-8

Chemical Property of 2-(2-Mercaptoethoxy)ethanol

Chemical Property:

• Boiling Point: 224.703 °C at 760 mmHg
• PKA: 9.62±0.10(Predicted)
• Flash Point: 89.697 °C
• PSA: 68.26000
• Density: 1.086 g/cm³
• LogP: 0.27110
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 122.04015073
• Heavy Atom Count: 7
• Complexity: 32.9

Purity/Quality:

99% ^*data from raw suppliers

2-(2-Mercaptoethoxy)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(COCCS)O
• Uses: 2-(2-Mercaptoethoxy)ethanol is used in preparation method of curing type hydrotreating catalyst.

Technology Process of 2-(2-Mercaptoethoxy)ethanol

There total 6 articles about 2-(2-Mercaptoethoxy)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(2-Chloroethoxy)ethanol (628-89-7) → 2-(2-mercaptoethoxy)ethanol (17643-17-3)

Guidance literature:

2-(2-Chloroethoxy)ethanol; With thiourea; sodium iodide; In acetonitrile; at 20 ℃; for 72h; Reflux;

With water; sodium hydroxide; In ethanol; for 24h; Reflux;

DOI:10.1039/c2cc37477c

Reference yield:

2-(2-Chloroethoxy)ethanol (628-89-7) → 2-(2-mercaptoethoxy)ethanol (17643-17-3) + [2-(2-mercaptoethoxy)-ethyl]-trimethylammonium toluene-4-sulfonate (728033-08-7)

Guidance literature:

With hydrogenchloride; sodium hydroxide; thiourea; In deoxygenated H₂O; water;

Reference yield:

deoxygenated triethylsilane + Deoxygenated trifluoroacetic acid + {2-[2-(2-tritylsulfanylethoxy)-ethoxy]-ethyl}-trimethylammonium toluene-4-sulfonate (728033-18-9) → 2-(2-mercaptoethoxy)ethanol (17643-17-3) + {2-[2-(2-mercaptoethoxy)-ethoxy]-ethyl}-trimethylammonium toluene-4-sulfonate (728033-14-5)

Guidance literature:

upstream raw materials:

2-(2-Chloroethoxy)ethanol

hydrogen sulfide

sodium ethanolate

{2-[2-(2-tritylsulfanylethoxy)-ethoxy]-ethyl}-trimethylammonium toluene-4-sulfonate

Downstream raw materials:

(Z)-2-((2-(2-hydroxyethoxy)ethyl)thio)-3-phenylacrylaldehyde

6-per-deoxy-6-per-(5-hydroxy-3-oxa-pentyl)thio-γ-cyclodextrin

Refernces

• 1、 Zhu, Liangliang,Yan, Hong,Ang, Chung Yen,Nguyen, Kim Truc,Li, Menghuan,Zhao, Yanli. "Photoswitchable supramolecular catalysis by interparticle host-guest competitive binding". supporting information. p. 13979 - 13983. Retrieved 2013/01/15.
• 2、 -. "Nanoparticles and Method to Control Nanoparticle Spacing". . . Retrieved 2009/04/24.