Stigmastane-3,6-diol

Base Information

• Chemical Name: Stigmastane-3,6-diol
• CAS No.: 112244-29-8
• Molecular Formula: C29H52O2
• Molecular Weight: 432.7
• Mol file: 112244-29-8.mol

Synonyms:Stigmastane-3,6-diol

Chemical Property of Stigmastane-3,6-diol

Chemical Property:

• Boiling Point: 524 °C at 760 mmHg
• Flash Point: 211.5 °C
• PSA: 40.46000
• Density: 0.99 g/cm³
• LogP: 7.07550

Purity/Quality:

98%min ^*data from raw suppliers

Stigmastane-3,6-diol ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Stigmastane-3,6-diol

There total 6 articles about Stigmastane-3,6-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

β-sitosterol (83-46-5) → stigmastane-3β,6α-diol (112244-29-8)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / Ambient temperature

2: 1.) BH₃*THF, 2.) aq. NaOH, aq. H₂O₂ / 1.) THF, RT, 6 h, 2.) THF, RT, 1 h

With pyridine; sodium hydroxide; borane-THF; dihydrogen peroxide;

DOI:10.1248/cpb.43.1813

Reference yield:

5α-stigmastene-(22t)-diol-(3β.6α) → stigmastane-3β,6α-diol (112244-29-8)

Guidance literature:

With acetic acid; platinum; Hydrogenation;

Reference yield:

stigmast-5-en-3-yl acetate (915-05-9,4651-54-1,29537-34-6,75023-86-8,120294-68-0,122331-55-9) → 5α-stigmastane-3β,6β-diol (171485-48-6) + stigmastane-3β,6α-diol (112244-29-8)

Guidance literature:

With sodium hydroxide; borane-THF; dihydrogen peroxide; Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, RT, 6 h, 2.) THF, RT, 1 h;

DOI:10.1248/cpb.43.1813

upstream raw materials:

stigmast-5-en-3-yl acetate

propan-1-ol

ethyl acetate

(24R)-3β-acetoxy-5α-hydroxystigmasan-6-one

Refernces