1-O-(4-Hydroxy-3-methoxyphenyl)-β-D-glucopyranose

Base Information

• Chemical Name: 1-O-(4-Hydroxy-3-methoxyphenyl)-β-D-glucopyranose
• CAS No.: 109194-60-7
• Molecular Formula: C13H18O8
• Molecular Weight: 302.281
• Mol file: 109194-60-7.mol

Synonyms:1-O-(3-Methoxy-4-hydroxyphenyl)-β-D-glucopyranose;1-O-(4-Hydroxy-3-methoxyphenyl)-β-D-glucopyranose;2-Methoxy-4-(β-D-glucopyranosyloxy)phenol;4-Hydroxy-3-methoxyphenyl β-D-glucopyranoside;Tachioside

Chemical Property of 1-O-(4-Hydroxy-3-methoxyphenyl)-β-D-glucopyranose

Chemical Property:

• Boiling Point: 577.4±50.0 °C(Predicted)
• PKA: 10.14±0.20(Predicted)
• PSA: 128.84000
• Density: 1.519±0.06 g/cm3(Predicted)
• LogP: -1.42050

Purity/Quality:

98%min ^*data from raw suppliers

Tachioside 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-O-(4-Hydroxy-3-methoxyphenyl)-β-D-glucopyranose

There total 3 articles about 1-O-(4-Hydroxy-3-methoxyphenyl)-β-D-glucopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methoxyhydroquinone (824-46-4) + 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide (572-09-8) → tachioside (109194-60-7) + tachioside (31427-08-4)

Guidance literature:

methoxyhydroquinone; 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide; With sodium hydroxide; In water; acetone; at 20 ℃; for 24h; Darkness;

In methanol; water; for 0.0833333h;

DOI:10.1021/acs.jafc.7b05674

Reference yield:

4-hydroxy-3-methoxyphenyl-1-O-(6′-O-galloyl)-β-D-glucopyranoside → tachioside (109194-60-7)

Guidance literature:

With water; for 3h; Ambient temperature; with tannase;

DOI:10.1016/S0031-9422(00)82367-5

Reference yield:

methanol (67-56-1) + 2-Methoxyhydroquinone 4-O-<6-O-(4-O-α-L-rhamnopyranosyl)-syringyl>-β-D-glucopyranoside (136112-50-0) → tachioside (109194-60-7) + Methyl syringate 4-O-α-L-rhamnopyranoside (130774-07-1)

Guidance literature:

With potassium carbonate; Ambient temperature;

DOI:10.1248/cpb.39.865

upstream raw materials:

methanol

2-Methoxyhydroquinone 4-O-<6-O-(4-O-α-L-rhamnopyranosyl)-syringyl>-β-D-glucopyranoside

methoxyhydroquinone

2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

Downstream raw materials:

3,4-dimethoxybenzyl alcohol O-β-D-glucopyranoside

methoxyhydroquinone

Refernces

• 1、 Sano,Sanada,Ida,Shoji. "Studies on the constituents of the bark of Kalopanax pictus Nakai". . p. 865 - 870. Retrieved 2007/10/02.