2-Epitormentic acid

Base Information

• Chemical Name: 2-Epitormentic acid
• CAS No.: 119725-19-8
• Molecular Formula: C₃₀H₄₈O₅
• Molecular Weight: 488.708
• Mol file: 119725-19-8.mol

Synonyms:2-Epitormentic acid

Chemical Property of 2-Epitormentic acid

Chemical Property:

• PSA: 97.99000
• LogP: 5.17520

Purity/Quality:

98% ^*data from raw suppliers

2-Epitormenticacid 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Epitormentic acid

There total 11 articles about 2-Epitormentic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.2%

2α,19α-dihydroxy-5α,9α-urs-12-en-3-one-28-oic acid-28-O-β-D-glucopyranosyl ester (1309589-79-4) → tormentic acid (53155-25-2,119725-19-8,13850-16-3) + rosamultin (95298-47-8,146356-82-3,88515-58-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 1h;

DOI:10.1016/j.phytochem.2014.03.002

Reference yield:

3-O-p-coumaroyltormentic acid → tormentic acid (53155-25-2,119725-19-8,13850-16-3)

Guidance literature:

3-O-p-coumaroyltormentic acid; With water; sodium hydroxide; at 20 ℃; for 15h;

With sulfuric acid; In water;

DOI:10.1016/j.bmc.2010.01.010

Reference yield:

serratolide → tormentic acid (53155-25-2,119725-19-8,13850-16-3)

Guidance literature:

With potassium hydroxide; In methanol; Heating;

DOI:10.1016/S0031-9422(98)00292-1

upstream raw materials:

3-O-trans-p-coumaroyltormentic acid

2α,19α-dihydroxy-5α,9α-urs-12-en-3-one-28-oic acid-28-O-β-D-glucopyranosyl ester

2α,3α,19α-trihydroxyurs-12-en-28-oic acid 28-β-D-glucopyranosyl ester

2α,3α-diacetoxy-19α-hydroxyurs-12-en-28-oic acid

Downstream raw materials:

polnolic acid

(2R,19R)-methyl 2-acetyloxy-19-hydroxy-3-oxours-12-en-28-carboxylate

methyl 2α,3α-diacetoxy-19α-hydroxyurs-12-en-28-oate

methyl 2α,3α,19-trihydroxyurs-12-en-28-oate

Refernces

• 1、 Lontsi, David,Ngounou, Ngninzeko Fernande,Tapondjou, Azefack Leon,Sondengam, Beibam Lucas,Bodo, Bernard,Martin, Marie-Therese. "An E-ring γ-lactone pentacyclic triterpene from Myrianthus serratus". . p. 2473 - 2476. Retrieved 1998.
• 2、 Rollinger, Judith M.,Kratschmar, Denise V.,Schuster, Daniela,Pfisterer, Petra H.,Gumy, Christel,Aubry, Evelyne M.,Brandst?tter, Sarah,Stuppner, Hermann,Wolber, Gerhard,Odermatt, Alex. "11β-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches". . p. 1507 - 1515. Retrieved 2010.