Pomolic acid 28-O-beta-D-glucopyranosyl ester

Base Information

• Chemical Name: Pomolic acid 28-O-beta-D-glucopyranosyl ester
• CAS No.: 83725-24-0
• Molecular Formula: C36H58O9
• Molecular Weight: 634.851
• Mol file: 83725-24-0.mol

Synonyms:

Chemical Property of Pomolic acid 28-O-beta-D-glucopyranosyl ester

Chemical Property:

• PSA: 156.91000
• LogP: 3.46290

Purity/Quality:

≥94% ^*data from raw suppliers

Pomolic acid beta-D-glucopyranosyl ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Pomolic Acid 28-?O-?β-?D-?Glucopyranosyl Ester is a triterpenoid with antiplatelet aggregation action that is isolated from the bark of Ilex rotunda.

Technology Process of Pomolic acid 28-O-beta-D-glucopyranosyl ester

There total 2 articles about Pomolic acid 28-O-beta-D-glucopyranosyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-O-sulfate of 28-O-β-D-glucopyranosyl pomolic acid → 3β,19α-dihydroxyurs-12-en-28-oic acid 28-β-D-glucopyranosyl ester (83725-24-0)

Guidance literature:

With pyridine; In 1,4-dioxane; at 80 ℃; for 5h;

DOI:10.1248/cpb.40.3138

Reference yield:

ilexoside II → 3β-[(α-L-arabinopyranosyl)oxy]-19α-hydroxyurs-12-en-28-oic acid 28-β-D-glucopyranosyl ester (136655-50-0,35286-58-9) + 3β,19α-dihydroxyurs-12-en-28-oic acid 28-β-D-glucopyranosyl ester (83725-24-0)

Guidance literature:

With acetate buffer; glycosidases from Turbo cornutus; at 37 ℃; for 408h;

DOI:10.1016/0031-9422(82)80145-3

Reference yield:

3β,19α-dihydroxyurs-12-en-28-oic acid 28-β-D-glucopyranosyl ester (83725-24-0) → polnolic acid (13849-91-7,19870-71-4,109008-39-1,119067-01-5)

Guidance literature:

With sodium dihydrogenphosphate; In ethanol; water; at 37 ℃; for 72h; cellulase, pH = 4.0;

DOI:10.1248/cpb.40.3138

Downstream raw materials:

pomolic acid 3β-acetate

polnolic acid

D-glucose

Refernces

• 1、 Nakanishi, Tsutomu,Terai, Hiroko,Nasu, Masao,Miura, Iwao,Yoneda, Kaisuke. "TWO TRITERPENOID GLYCOSIDES FROM LEAVES OF ILEX CORNUTA". . p. 1373 - 1378. Retrieved 2007/10/02.