12-Hydroxyabietic acid

Base Information

• Chemical Name: 12-Hydroxyabietic acid
• CAS No.: 3484-61-5
• Molecular Formula: C20H30O3
• Molecular Weight: 318.45000
• Mol file: 3484-61-5.mol

Synonyms:3-oxo-12|A-hydroxy-5|A-cholan-24-oic acid;12-hydroxyabietic acid;12alpha-Hydroxy-3-oxo-5beta-cholanoic acid;6-Hydroxy-abietinsaeure;

Chemical Property of 12-Hydroxyabietic acid

Chemical Property:

• PSA: 57.53000
• LogP: 4.17700

Purity/Quality:

99% ^*data from raw suppliers

12-Hydroxyabieticacid ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 12-Hydroxyabietic acid

There total 5 articles about 12-Hydroxyabietic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

levopimaric acid (79-54-9) → 12α-Hydroxyabietinsaeure (3484-61-5)

Guidance literature:

With sodium hydroxide; sodium hypochlorite;

Reference yield:

p-nitrophenyl 12α-hydroxy-7,13-abietatrien-18-oate → 12α-Hydroxyabietinsaeure (3484-61-5)

Guidance literature:

With sodium hydroxide; In acetone; for 2h; Yield given; Ambient temperature;

DOI:10.1016/S0040-4020(01)88015-7

Reference yield:

abietic acid (514-10-3) → 12α-Hydroxyabietinsaeure (3484-61-5)

Guidance literature:

With selenium(IV) oxide;

DOI:10.1016/0040-4020(67)85075-0

upstream raw materials:

abietic acid

levopimaric acid

Refernces

• 1、 Krohn, Karsten,Budianto, Emil,Floerke, Ulrich,Hausen, Bjoern M.. "Investigation of the Allergenic Principles from Colophony: Autoxidation, Synthesis, and Sensitization". . p. 911 - 920. Retrieved 2007/10/02.