Octacosyl (E)-ferulate

Base Information

• Chemical Name: Octacosyl (E)-ferulate
• CAS No.: 101959-37-9
• Molecular Formula: C38H66 O4
• Molecular Weight: 586.94
• Mol file: 101959-37-9.mol

Synonyms:2-Propenoicacid, 3-(4-hydroxy-3-methoxyphenyl)-, octacosyl ester, (E)-; Erythrinasinate B;Octacosyl (E)-ferulate

Chemical Property of Octacosyl (E)-ferulate

Chemical Property:

• Melting Point: 74-75 °C
• Boiling Point: 659.1±40.0 °C(Predicted)
• PKA: 9.75±0.20(Predicted)
• PSA: 55.76000
• Density: 0.948±0.06 g/cm3(Predicted)
• LogP: 12.11970

Purity/Quality:

98%min ^*data from raw suppliers

Octacosyl(E)-ferulate ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Octacosyl (E)-ferulate

There total 3 articles about Octacosyl (E)-ferulate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methoxy-4-(tetrahydropyran-2-yloxy)benzaldehyde (91471-08-8) → octacosyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate (101959-37-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 40 percent / piperidine, aniline / pyridine / 15 h / 70 - 80 °C

2: DCC / pyridine / 50 - 55 °C

3: 1M HCl / tetrahydrofuran / 1 h / Ambient temperature

With hydrogenchloride; dicyclohexyl-carbodiimide; piperidine; aniline; In tetrahydrofuran; pyridine;

DOI:10.1016/0031-9422(92)83695-U

Reference yield:

(E)-3-[3-Methoxy-4-(tetrahydro-pyran-2-yloxy)-phenyl]-acrylic acid octacosyl ester → octacosyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate (101959-37-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 1h; Yield given; Ambient temperature;

DOI:10.1016/0031-9422(92)83695-U

Reference yield:

(E)-3-<3-Methoxy-4-(tetrahydropyran-2-yloxy)phenyl>prop-2-enoic acid (145205-03-4) → octacosyl (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate (101959-37-9)

Guidance literature:

Multi-step reaction with 2 steps

1: DCC / pyridine / 50 - 55 °C

2: 1M HCl / tetrahydrofuran / 1 h / Ambient temperature

With hydrogenchloride; dicyclohexyl-carbodiimide; In tetrahydrofuran; pyridine;

DOI:10.1016/0031-9422(92)83695-U

upstream raw materials:

3-methoxy-4-(tetrahydropyran-2-yloxy)benzaldehyde

(E)-3-<3-Methoxy-4-(tetrahydropyran-2-yloxy)phenyl>prop-2-enoic acid

Downstream raw materials:

octacosanyl acetoxyferulate

Refernces