5,7-diacetoxy-3,4',8-trimethoxyflavone

Base Information

• Chemical Name: 5,7-diacetoxy-3,4',8-trimethoxyflavone
• CAS No.: 5128-43-8
• Molecular Formula: C22H20O9
• Molecular Weight: 428.395
• Hs Code.: 2915390090
• Mol file: 5128-43-8.mol

Synonyms:5,7-dihydroxy-3,4',8-trimethoxyflavone diacetate;5,7-Diacetoxy-3,8,4'-trimethoxy-flavon;5,7-diacetoxy-3-pyridin-3-yl-chromen-2-one;3-O-Methyl-prudomestin-diacetat;

Chemical Property of 5,7-diacetoxy-3,4',8-trimethoxyflavone

Chemical Property:

• PSA: 110.50000
• LogP: 3.33640
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

5,7-Diacetoxy-3,4',8-Trimethoxyflavone 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,7-diacetoxy-3,4',8-trimethoxyflavone

There total 3 articles about 5,7-diacetoxy-3,4',8-trimethoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,7-dihydroxy-3,8-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one (1570-09-8) + acetic anhydride (108-24-7) → 5,7-dihydroxy-3,4',8-trimethoxyflavone diacetate (5128-43-8)

Guidance literature:

With pyridine;

Reference yield:

7-benzyloxy-5-hydroxy-3,8-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one (1570-10-1) → 5,7-dihydroxy-3,4',8-trimethoxyflavone diacetate (5128-43-8)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous hydrochloric acid; acetic acid

2: pyridine

With pyridine; hydrogenchloride; acetic acid;

Reference yield:

→ 5,7-dihydroxy-3,4',8-trimethoxyflavone diacetate (5128-43-8)

Guidance literature:

5,7-Dihydroxy-3,8,4'-trimethoxy-flavon (IIa), Acetanhydrid, HClO4;

upstream raw materials:

5,7-dihydroxy-3,8-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one

acetic anhydride

7-benzyloxy-5-hydroxy-3,8-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one