9-O-Acetyl-4,4'-di-O-methyllariciresil

Base Information

• Chemical Name: 9-O-Acetyl-4,4'-di-O-methyllariciresil
• CAS No.: 73354-15-1
• Molecular Formula: C24H30O7
• Molecular Weight: 430.49100
• Mol file: 73354-15-1.mol

Synonyms:

Chemical Property of 9-O-Acetyl-4,4'-di-O-methyllariciresil

Chemical Property:

• Boiling Point: 534.4±50.0 °C(Predicted)
• PSA: 72.45000
• Density: 1.145±0.06 g/cm3(Predicted)
• LogP: 3.83050

Purity/Quality:

98%min ^*data from raw suppliers

9-O-Acetyl-4,4'-di-O-methyllariciresinol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-O-Acetyl-4,4'-di-O-methyllariciresil

There total 8 articles about 9-O-Acetyl-4,4'-di-O-methyllariciresil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H30O7 (73354-15-1) → ((2S,3R,4R)-4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrofuran-3-yl)methyl acetate (73354-15-1) + (4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrofuran-3-yl)methyl acetate (73354-15-1)

Guidance literature:

With iodosylbenzene; C₇₀H₅₀MnN₂O₄⁽¹⁺⁾*F₆P^(1-); In dichloromethane; at -40 ℃; for 5h; Overall yield = 44 percent; Overall yield = 18.9 mg; Resolution of racemate;

DOI:10.1021/jacs.0c09636

Reference yield:

C24H30O7 (73354-15-1) → ((2S,3R,4R)-4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrofuran-3-yl)methyl acetate (73354-15-1) + (4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrofuran-3-yl)methyl acetate (73354-15-1)

Guidance literature:

With iodosylbenzene; C₇₀H₅₀MnN₂O₄⁽¹⁺⁾*F₆P^(1-); In dichloromethane; at -40 ℃; for 5h; Overall yield = 44 percent; Overall yield = 18.9 mg; Resolution of racemate;

DOI:10.1021/jacs.0c09636

Reference yield:

3'-Hydroxymethyleugenol (40918-90-9,70570-23-9,18523-76-7) → C24H30O7 (73354-15-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / dichloromethane

2: dmap; pyridine

With pyridine; dmap; N-Bromosuccinimide; In dichloromethane;

DOI:10.1021/jacs.0c09636

upstream raw materials:

3'-Hydroxymethyleugenol

(4-(3,4-dimethoxybenzyl)-2-(3,4-dimethoxyphenyl)tetrahydrofuran-3-yl)methanol

acetic anhydride

Refernces