9,19-Cyclo-5α-lanost-25-ene-3β,24-diol

Base Information

• Chemical Name: 9,19-Cyclo-5α-lanost-25-ene-3β,24-diol
• CAS No.: 10388-48-4
• Molecular Formula: C₃₀H₅₀O₂
• Molecular Weight: 442.726
• Mol file: 10388-48-4.mol

Synonyms:9,19-Cyclo-9b-lanost-25-ene-3b,24-diol (7CI,8CI);1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, 9,19-cyclolanost-25-ene-3,24-diolderiv.; (24RS)-Cycloart-25-ene-3b,24-diol; 25-Dehydro-3b,24x-dihydroxycycloartane;9,19-Cycloart-25-ene-3b,24x-diol; 9,19-Cyclolanost-25-ene-3b,24-diol; Cycloart-25-ene-3b,24-diol

Chemical Property of 9,19-Cyclo-5α-lanost-25-ene-3β,24-diol

Chemical Property:

• Melting Point: 153 °C (CHCl3)
• Boiling Point: 537.7±23.0 °C(Predicted)
• PKA: 14.48±0.20(Predicted)
• PSA: 40.46000
• Density: 1.05±0.1 g/cm3(Predicted)
• LogP: 7.13970

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cycloart-25-ene-3β,24-diol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9,19-Cyclo-5α-lanost-25-ene-3β,24-diol

There total 5 articles about 9,19-Cyclo-5α-lanost-25-ene-3β,24-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(24R/S)-9,19-cyclolanost-25-ene-3β,24-diol diacetate → cycloart-25-en-3b,24-diol (99946-06-2,99946-09-5,10388-48-4)

Guidance literature:

With potassium hydroxide; In methanol; for 0.0166667h; microwave irradiation;

Reference yield: 2.2%

cycloartenol (469-38-5) → cycloart-24-en-3-one (511-63-7) + cycloart-25-en-3b,24-diol (99946-06-2,99946-09-5,10388-48-4) + cycloartan-3β,24ξ,25-triol

Guidance literature:

With Glomerella fusarioides IFO 8831 mycelium; In methanol; dimethyl sulfoxide; at 20 ℃; for 240h;

DOI:10.1021/np058120d

Reference yield:

9,19-cyclolanostan-3-one (4936-10-1) → cycloart-25-en-3b,24-diol (99946-06-2,99946-09-5,10388-48-4)

Guidance literature:

Multi-step reaction with 3 steps

1: LiAlH₄ / diethyl ether

2: 100 percent / pyridine

3: 1.) pyridine, hematoporphyrine, O₂, 2.) LiAlH₄ / 1.) irradiation, 2 h, 2.) ether, RT, 2 h

With pyridine; lithium aluminium tetrahydride; hematoporphyrin; oxygen; In diethyl ether;

DOI:10.1055/s-2006-957893

upstream raw materials:

cycloartanyl acetate

cycloartanol

9,19-cyclolanostan-3-one

cycloartenol

Refernces

• 1、 Jayakumar,Ajithabai,Santhosh,Veena,Nairt, Mangalam S.. "Microwave assisted acetylation and deacetylation studies on the triterpenes isolated from Dysoxylum malabaricum and Dysoxylum beddomei". . p. 429 - 431. Retrieved 2007/10/03.