3beta-Hydroxyporiferast-5-en-7-one

Base Information

• Chemical Name: 3beta-Hydroxyporiferast-5-en-7-one
• CAS No.: 145163-97-9
• Molecular Formula: C₂₉H₄₈O₂
• Molecular Weight: 428.699
• Mol file: 145163-97-9.mol

Synonyms:(24S)-3b-Hydroxy-24-ethylcholest-5-en-7-one;24(S)-3b-Hydroxystigmast-5-en-7-one

Chemical Property of 3beta-Hydroxyporiferast-5-en-7-one

Chemical Property:

• PSA: 37.30000
• LogP: 7.20380

Purity/Quality:

98%min ^*data from raw suppliers

3beta-Hydroxyporiferast-5-en-7-one ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3beta-Hydroxyporiferast-5-en-7-one

There total 16 articles about 3beta-Hydroxyporiferast-5-en-7-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

7-keto-β-sitosterol acetate → 3β-hydroxystigmast-5-en-7-one (2034-74-4,75521-66-3,88548-08-7,145163-97-9)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; methanol; water; at 20 ℃; for 2h;

DOI:10.1021/jf506361r

Reference yield: 97.0%

(24R)-3β-acetoxystigmast-5-en-7-one (18376-53-9) → 3β-hydroxystigmast-5-en-7-one (2034-74-4,75521-66-3,88548-08-7,145163-97-9)

Guidance literature:

With sodium methylate; In methanol; chloroform; at 20 ℃; for 2h;

DOI:10.1021/jm1007769

Reference yield: 68.0%

β-sitosterol (83-46-5) → 3β-hydroxystigmast-5-en-7-one (2034-74-4,75521-66-3,88548-08-7,145163-97-9)

Guidance literature:

With N-hydroxyphthalimide; oxygen; cobalt(II) acetate; manganese(II) acetate; In 1,4-dioxane; at 20 ℃; for 8h; under 760.051 Torr;

DOI:10.1039/b915737a

upstream raw materials:

stigmast-3β,7β-dihydroxyl-5-ene

7-oxo-poriferast-5-en-3β-yl-acetate

stigmast-3β,7α-dihydroxyl-5-ene

3β-acetoxysitosterol

Downstream raw materials:

5-stigmasten-3β,7β-diol

poriferasta-3,5-dien-7-one

22-dihydrospinasterol

Refernces

• 1、 Kimura,Yasukawa,Takido,Akihisa,Tamura. "Inhibitory effect of some oxygenated stigmastane-type sterols on 12-O- tetradecanoylphorbol-13-acetate-induced inflammation in mice". . p. 1617 - 1619. Retrieved 1995.
• 2、 Gomes, Suzane Quintana,Salles, Airton G.. "A metal-free approach to access ketones, amides, and nitriles employing TBAI/TBHP oxidative system in water". supporting information. p. 3389 - 3399. Retrieved 2019/11/05.
• 3、 Zhu, Yingdong,Soroka, Dominique,Sang, Shengmin. "Oxyphytosterols as active ingredients in wheat bran suppress human colon cancer cell growth: Identification, chemical synthesis, and biological evaluation". . p. 2267 - 2276. Retrieved 2015/03/14.