2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

Base Information

• Chemical Name: 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine
• CAS No.: 627536-09-8
• Molecular Formula: C₁₇H₁₀ClFN₆
• Molecular Weight: 352.758
• European Community (EC) Number: 636-373-7
• DSSTox Substance ID: DTXSID60438042
• Wikidata: Q27088765
• Pharos Ligand ID: 76WNY8C95W3W
• ChEMBL ID: CHEMBL238125
• Mol file: 627536-09-8.mol

Synonyms:SD-208

Chemical Property of 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

Chemical Property:

• Vapor Pressure: 1.17E-08mmHg at 25°C
• Refractive Index: 1.717
• Boiling Point: 460.4°C at 760 mmHg
• Flash Point: 232.2°C
• PSA: 76.48000
• Density: 1.487
• LogP: 4.09090
• Storage Temp.: 2-8°C
• Solubility.: DMSO: >5mg/mL
• XLogP3: 3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 352.0639502
• Heavy Atom Count: 25
• Complexity: 437

Purity/Quality:

98%,99%, ^*data from raw suppliers

SD 208 ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)C2=NC3=NC=CN=C3C(=N2)NC4=CC=NC=C4)F
• Uses: SD-208 was used to inhibit the activity of ALK5 kinase in bovine retinal vascular cells.2

Technology Process of 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine

There total 1 articles about 2-(5-chloro-2-fluorophenyl)-N-(pyridin-4-yl)pteridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine (817629-63-3,627536-09-8)

Guidance literature:

Refernces