MCPB METHYL ESTER

Base Information

• Chemical Name: MCPB METHYL ESTER
• CAS No.: 57153-18-1
• Molecular Formula: C12H15ClO3
• Molecular Weight: 242.702
• Mol file: 57153-18-1.mol

Synonyms:Butanoic acid, 4-(2-methyl-4-chlorophenoxy)-, methyl ester;Methyl 4-(4-chloro-2-methylphenoxy)butanoate;MCPB METHYL ESTER;4-(4-CHLORO-O-TOLYLOXY) BUTRYRIC ACID METHYLESTER;4-(4-CHLORO-O-TOLYLOXY)-BUTYRIC ACID METHYLESTER;4-(4-CHLORO-2-METHYLPHENOXY)-BUTYRIC ACID, METHYL ESTER;MCPB METHYL ESTER, 500MG, NEAT;MCPB-METHYL ESTER PESTANAL(METHYL 4-(4-&

Chemical Property of MCPB METHYL ESTER

Chemical Property:

• Vapor Pressure: 8.55E-05mmHg at 25°C
• Refractive Index: 1.508
• Boiling Point: 340.5°Cat760mmHg
• Flash Point: 135.3°C
• PSA: 35.53000
• Density: 1.149g/cm³
• LogP: 2.98040
• Storage Temp.: 0-6°C

Purity/Quality:

98%Min ^*data from raw suppliers

MCPB-methylester ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: MCPB-methyl ester

Technology Process of MCPB METHYL ESTER

There total 6 articles about MCPB METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

diphenylmethylsilanecarboxylic acid (18414-58-9) + sodium methylate (124-41-4) + 4-chloro-1-(3-iodopropoxy)-2-methylbenzene → methyl 4-chloro-2-methylphenoxybutyrate (57153-18-1)

Guidance literature:

With potassium fluoride; propyl cyanide; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; (2-morpholino-N-(quinolin-8-yl)acetamido)nickel(II) chloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/jacs.1c09170

Reference yield:

methyl 4-(2-methylphenoxy)butyrate → methyl 4-chloro-2-methylphenoxybutyrate (57153-18-1)

Guidance literature:

With sulfuryl dichloride; 2,2',4,4',6,6'-hexamethyldiphenyl sulfide; chlorine; at 40 ℃; for 0.5h; Reagent/catalyst; Temperature;

Reference yield:

methyl 4-chlorobutyrate (3153-37-5) → methyl 4-chloro-2-methylphenoxybutyrate (57153-18-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide / 5,5-dimethyl-1,3-cyclohexadiene / Reflux

1.2: 0.5 h / 70 °C

2.1: chlorine; 2,2',4,4',6,6'-hexamethyldiphenyl sulfide; sulfuryl dichloride / 0.5 h / 40 °C

With sulfuryl dichloride; 2,2',4,4',6,6'-hexamethyldiphenyl sulfide; chlorine; potassium hydroxide; In 5,5-dimethyl-1,3-cyclohexadiene;

upstream raw materials:

ortho-cresol

methyl 4-chlorobutyrate

MCPB

diphenylmethylsilanecarboxylic acid

Refernces

• 1、 -. "A phenoxy carboxylic acid ester herbicide preparation method (by machine translation)". . . Retrieved 2019/01/08.