4-(2,6-Dichloropyrimidin-4-yl)morpholine

Base Information Edit

Chemical Name:4-(2,6-Dichloropyrimidin-4-yl)morpholine
CAS No.:52127-83-0
Molecular Formula:C8H9Cl2N3O
Molecular Weight:234.085
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10469008
Wikidata:Q82296561
Mol file:52127-83-0.mol

Synonyms:4-(2,6-Dichloropyrimidin-4-yl)morpholine;52127-83-0;4-(2,6-Dichloro-pyrimidin-4-yl)-morpholine;2,4-dichloro-6-morpholinopyrimidine;4-(2,6-dichloropyrimidin-4-yl)-morpholine;4-(2,6-Dichloro-4-pyrimidyl)morpholine;MFCD09746259;10197-13-4;2,4-Dichloro-6-(morpholin-4-yl)pyrimidine;SCHEMBL856815;AMY1933;DTXSID10469008;QGGYMWHOBGSQCF-UHFFFAOYSA-N;CCA12783;6-Morpholino-2,4-dichloropyrimidine;4-NITROINDOLE-3-CARBOXYLICACID;AKOS016003632;AS-64548;SY034855;2,4-Dichloro-6-(4-morpholino)pyrimidine;4-(2,6-dichloro-4-pyrimidinyl)morpholine;CS-0129824;D4571;EN300-817107;F19709;A828938;J-513271;4-(2,6-dichloro-pyrimidin-4-yl)-morpholine, AldrichCPR

Suppliers and Price of 4-(2,6-Dichloropyrimidin-4-yl)morpholine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2,6-Dichloropyrimidin-4-yl)-morpholine
250mg
$ 165.00

TCI Chemical
4-(2,6-Dichloro-4-pyrimidyl)morpholine >98.0%(GC)
5g
$ 476.00

TCI Chemical
4-(2,6-Dichloro-4-pyrimidyl)morpholine >98.0%(GC)
1g
$ 139.00

SynQuest Laboratories
2,4-Dichloro-6-morpholinopyrimidine
5 g
$ 650.00

SynChem
4-(2,6-Dichloro-pyrimidin-4-yl)-morpholine 95+%
1 g
$ 95.00

SynChem
4-(2,6-Dichloro-pyrimidin-4-yl)-morpholine 95+%
10 g
$ 495.00

SynChem
4-(2,6-Dichloro-pyrimidin-4-yl)-morpholine 95+%
5 g
$ 325.00

Medical Isotopes, Inc.
4-(2,6-Dichloropyrimidin-4-yl)-morpholine
2.5 g
$ 2200.00

Crysdot
4-(2,6-Dichloropyrimidin-4-yl)morpholine 95+%
10g
$ 461.00

Chem-Impex
4-(2,6-Dichloro-4-pyrimidyl)morpholine,≥98%(GC) ≥98%(GC)
1G
$ 159.06

Total 22 raw suppliers

Chemical Property of 4-(2,6-Dichloropyrimidin-4-yl)morpholine Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.577
Boiling Point:396.137 °C at 760 mmHg
PKA:0.03±0.39(Predicted)
Flash Point:193.377 °C
PSA：38.25000
Density:1.435 g/cm³
LogP:1.68500
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Dichloromethane, Ethyl Acetate
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:233.0122673
Heavy Atom Count:14
Complexity:189

Purity/Quality:

96.0%Min ^*data from raw suppliers

4-(2,6-Dichloropyrimidin-4-yl)-morpholine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=CC(=NC(=N2)Cl)Cl
Uses 4-(2,6-DICHLOROPYRIMIDIN-4-YL)MORPHOLINE is a reactant used in the preparation of α-azinylalkylamino-substituted pyrimidines as JAK2 inhibitors. A reactant used in the preparation of α-azinylalkylamino-substituted pyrimidines as JAK2 inhibitors.

Technology Process of 4-(2,6-Dichloropyrimidin-4-yl)morpholine

There total 4 articles about 4-(2,6-Dichloropyrimidin-4-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%