2,4-DICHLOROPHENOXYACETIC ACID HYDRAZIDE

Base Information

• Chemical Name: 2,4-DICHLOROPHENOXYACETIC ACID HYDRAZIDE
• CAS No.: 28236-62-6
• Molecular Formula: C8H8Cl2N2O2
• Molecular Weight: 235.07
• Hs Code.: 2928000090
• Mol file: 28236-62-6.mol

Synonyms:2,4-Dichlorophenoxyacetic acid hydrazide;Aceticacid, (2,4-dichlorophenoxy)-, hydrazide (8CI,9CI);(2,4-Dichlorophenoxy)aceticacid hydrazide;(2,4-Dichlorophenoxy)acetyl hydrazide;2,4-D hydrazide;2,4-Dichlorophenoxyacethydrazide;2,4-Dichlorophenoxyacetylhydrazine;H-2,4-D;NSC 222172;

Chemical Property of 2,4-DICHLOROPHENOXYACETIC ACID HYDRAZIDE

Chemical Property:

• Appearance/Colour: light beige crystalline powder
• Vapor Pressure: 3E-08mmHg at 25°C
• Melting Point: 153-157 °C
• Refractive Index: 1.581
• Boiling Point: 448.8 °C at 760 mmHg
• Flash Point: 225.2 °C
• PSA: 64.35000
• Density: 1.438 g/cm³
• LogP: 2.45330
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4-Dichlorophenoxyacetic acid hydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 36/37/38-22
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-DICHLOROPHENOXYACETIC ACID HYDRAZIDE

There total 6 articles about 2,4-DICHLOROPHENOXYACETIC ACID HYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

ethyl 2,4-dichlorophenoxyacetate (533-23-3) → 2,4-dichlorophenoxyacetylhydrazine (28236-62-6)

Guidance literature:

With hydrazine hydrate; In ethanol; Reflux;

DOI:10.1016/j.ejmech.2013.08.027

Reference yield: 90.0%

2,4-Dichlorophenoxyacetic acid (94-75-7,89300-30-1) → 2,4-dichlorophenoxyacetylhydrazine (28236-62-6)

Guidance literature:

With hydrazine hydrate; Vilsmeier reagent; triethylamine; In dichloromethane; at 20 ℃; for 7h;

DOI:10.1007/s11164-016-2738-x

Reference yield:

methyl 2,4-dichlorophenoxyacetate (1928-38-7) → 2,4-dichlorophenoxyacetylhydrazine (28236-62-6)

Guidance literature:

With hydrazine hydrate; In ethanol; Heating;

DOI:10.1248/cpb.22.2778

upstream raw materials:

ethyl 2,4-dichlorophenoxyacetate

methyl 2,4-dichlorophenoxyacetate

2,4-Dichlorophenoxyacetic acid

2,4-dichlorophenol

Downstream raw materials:

(2,4-dichloro-phenoxy)-acetic acid-(2-chloro-benzylidenehydrazide)

(2,4-dichloro-phenoxy)-acetic acid-(2,2,2-trichloro-ethylidenehydrazide)

(2,4-dichloro-phenoxymethyl)-carbamic acid isopropyl ester

(2,4-dichloro-phenoxymethyl)-carbamic acid-(2-chloro-ethyl ester)

Refernces

• 1、 Lokanath,Sridhar,Shashidhara Prasad,Nagaraja,Mohan Rao. "(2,4-Dichlorophenoxy)acetohydrazide". . p. 669 - 670. Retrieved 1998.
• 2、 Jupudi, Srikanth,Azam, Mohammed Afzal,Wadhwani, Ashish. "Design, synthesis and molecular modelling of phenoxyacetohydrazide derivatives as Staphylococcus aureus MurD inhibitors". . p. 1221 - 1235. Retrieved 2020/10/09.
• 3、 Wang, Wei,Zheng, Xiao-Rui,Huang, Xiao-Ying,Mao, Ming-Zhen,Liu, Kang-Yun,Xue, Chao,Wang, Lie-Ping,Ning, Bin-Ke. "Synthesis and Insecticidal Evaluation of Novel N-pyridylpyrazole Derivatives Containing Diacylhydrazine/1,3,4-Oxadiazole Moieties". . p. 1330 - 1336. Retrieved 2019/01/30.