2-Bromo-N,N-dipropylbenzenesulphonamide

Base Information

• Chemical Name: 2-Bromo-N,N-dipropylbenzenesulphonamide
• CAS No.: 65000-11-5
• Molecular Formula: C12H18 Br N O2 S
• Molecular Weight: 320.25
• Hs Code.: 2935009090
• Mol file: 65000-11-5.mol

Synonyms:2-Bromo-N,N-dipropylbenzenesulphonamide;2-Bromo-N,N-dipropylbenzenesulfonamide;N, N-Dipropyl 2-bromobenzenesulfonamide

Chemical Property of 2-Bromo-N,N-dipropylbenzenesulphonamide

Chemical Property:

• Vapor Pressure: 2.37E-06mmHg at 25°C
• Refractive Index: 1.544
• Boiling Point: 392°C at 760 mmHg
• Flash Point: 190.8°C
• PSA: 45.76000
• Density: 1.35g/cm³
• LogP: 4.34060
• Storage Temp.: 2-8°C

Purity/Quality:

95-99% ^*data from raw suppliers

2-Bromo-N,N-dipropylbenzenesulfonamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-N,N-dipropylbenzenesulphonamide

There total 2 articles about 2-Bromo-N,N-dipropylbenzenesulphonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

o-bromobenzenesulfonyl chloride (2905-25-1) + di-n-propylamine (142-84-7) → 2-bromo-N,N-dipropylbenzenesulfonamide (65000-11-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1002/adsc.201300795

Reference yield:

bromobenzene (108-86-1,52753-63-6) → 2-bromo-N,N-dipropylbenzenesulfonamide (65000-11-5)

Guidance literature:

Multi-step reaction with 2 steps

1: chlorosulfonic acid / Schlenk technique; Inert atmosphere

2: triethylamine / dichloromethane / 12 h / 0 - 20 °C / Schlenk technique; Inert atmosphere

With chlorosulfonic acid; triethylamine; In dichloromethane;

DOI:10.1002/adsc.201300795

Reference yield: 40.0%

2-bromo-N,N-dipropylbenzenesulfonamide (65000-11-5) → (E)-N-propenyl-N-propylbenzenesulfonamide

Guidance literature:

With palladium diacetate; potassium pivalate; In N,N-dimethyl acetamide; at 150 ℃; for 16h; Schlenk technique; Inert atmosphere;

DOI:10.1002/adsc.201300795

upstream raw materials:

o-bromobenzenesulfonyl chloride

di-n-propylamine

bromobenzene

Refernces