2'-O-Tosyl cAMP

Base Information

• Chemical Name: 2'-O-Tosyl cAMP
• CAS No.: 77056-11-2
• Molecular Formula: C₁₇H₁₈N₅O₈PS
• Molecular Weight: 483.398
• Mol file: 77056-11-2.mol

Synonyms:2'-O-Tosyl cAMP

Chemical Property of 2'-O-Tosyl cAMP

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2'-O-Tosyl cAMP

There total 1 articles about 2'-O-Tosyl cAMP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

cAMP (60-92-4) + p-toluenesulfonyl chloride (98-59-9) → 2'-O-Tosyl cAMP (77056-11-2)

Guidance literature:

With sodium hydroxide; In 1,4-dioxane; Ambient temperature;

DOI:10.1248/cpb.38.3147

Reference yield: 78.0%

2'-O-Tosyl cAMP (77056-11-2) + acetaldehyde (75-07-0,9002-91-9) → N6-Ethyl-2'-O-tosyl cAMP (132398-91-5)

Guidance literature:

With sodium cyanoborohydride; In acetic acid; at 50 ℃;

DOI:10.1248/cpb.38.3147

Reference yield: 54.0%

2'-O-Tosyl cAMP (77056-11-2) + butyraldehyde (123-72-8) → N6-Butyl-2'-O-tosyl cAMP (132398-93-7)

Guidance literature:

With sodium cyanoborohydride; In acetic acid; at 50 ℃;

DOI:10.1248/cpb.38.3147

upstream raw materials:

cAMP

p-toluenesulfonyl chloride

Downstream raw materials:

Toluene-4-sulfonic acid (4aR,6R,7R,7aR)-6-(6-dibutylamino-purin-9-yl)-2-hydroxy-2-oxo-tetrahydro-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl ester

Toluene-4-sulfonic acid (4aR,6R,7R,7aR)-6-(6-dipropylamino-purin-9-yl)-2-hydroxy-2-oxo-tetrahydro-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-7-yl ester

N⁶-Ethyl-2'-O-tosyl cAMP

N⁶-Propyl-2'-O-tosyl cAMP

Refernces