(4-Ethoxybenzyl)triphenylphosphonium bromide

Base Information

• Chemical Name: (4-Ethoxybenzyl)triphenylphosphonium bromide
• CAS No.: 82105-88-2
• Molecular Formula: Br*C₂₇H₂₆OP
• Molecular Weight: 477.381
• Hs Code.: 2931 39 90
• DSSTox Substance ID: DTXSID90369138
• Mol file: 82105-88-2.mol

Synonyms:82105-88-2;(4-Ethoxybenzyl)triphenylphosphonium bromide;4-Ethoxybenzyltriphenylphosphonium Bromide;(4-ethoxyphenyl)methyl-triphenylphosphanium;bromide;SCHEMBL2449254;DTXSID90369138;MZBKKJRCQNVENM-UHFFFAOYSA-M;MFCD00011834;AKOS015832984;p-ethoxybenzyltriphenylphosphonium bromide;(4-Ethoxybenzyl)triphenylphosphoniumbromide;CS-0322399;E0421;FT-0604763;FT-0604764;(4-ethoxybenzyl)(triphenyl)phosphonium bromide;D90511;[(4-ethoxyphenyl)methyl]triphenylphosphanium bromide;[(4-Ethoxyphenyl)methyl](triphenyl)phosphanium bromide

Chemical Property of (4-Ethoxybenzyl)triphenylphosphonium bromide

Chemical Property:

• Appearance/Colour: WHITE POWDER
• Melting Point: 214-215 °C(lit.)
• PSA: 22.82000
• LogP: 2.58340
• Storage Temp.: 0-6°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 476.09047
• Heavy Atom Count: 30
• Complexity: 406

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Ethoxybenzyltriphenylphosphonium Bromide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=CC=C(C=C1)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
• Uses: 4-Ethoxybenzyltriphenylphosphonium Bromide has been used to enhance the transport of ionized chloraphenicol succinate across an artificial membrane. It is commonly used as a Wittig reagent.

Technology Process of (4-Ethoxybenzyl)triphenylphosphonium bromide

There total 1 articles about (4-Ethoxybenzyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-ethoxybenzyl bromide (2606-57-7) + triphenylphosphine (603-35-0) → (4-ethoxy)benzyltriphenylphosphonium bromide (82105-88-2)

Guidance literature:

In xylene; Yield given;

DOI:10.1016/S0040-4020(97)00871-5

Reference yield:

(4-ethoxy)benzyltriphenylphosphonium bromide (82105-88-2) → ethyl (E)-3-(4-ethoxystyryl)-2-methyl-1H-indole-1-carboxylate

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hexamethyldisilazane / toluene; tetrahydrofuran / 0.33 h / -78 - 0 °C

1.2: 12 h / -78 - 20 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C

2.2: -78 - 20 °C

With n-butyllithium; sodium hexamethyldisilazane; In tetrahydrofuran; hexane; toluene;

DOI:10.1002/adsc.201700280

Reference yield:

potassium thioacyanate (333-20-0) + (4-ethoxy)benzyltriphenylphosphonium bromide (82105-88-2) → [Ph3PBnOEt][SCN]

Guidance literature:

In acetonitrile; at 20 ℃; for 48h;

DOI:10.1016/j.jinorgbio.2011.09.035

upstream raw materials:

4-ethoxybenzyl bromide

triphenylphosphine

Refernces