5-AZIDO-5-DEOXY-D-FRUCTOSE

Base Information

• Chemical Name: 5-AZIDO-5-DEOXY-D-FRUCTOSE
• CAS No.: 94801-02-2
• Molecular Formula: C6H11 N3 O5
• Molecular Weight: 205.17
• Hs Code.: 2932999099
• Mol file: 94801-02-2.mol

Synonyms:5'-Deoxy-5'-azidoadenosine; 5-azido-5-deoxy-D-fructopyranose; 5'-azido-5'-deoxyAdo; 5'-Deoxy-5'-azido-adenosin; 5'-Azidoadenosine; 5'-Azido-5'-desoxy-adenosin; 5'-azido-5'-deoxyadenosine; 查看更多英文别名 收起

Chemical Property of 5-AZIDO-5-DEOXY-D-FRUCTOSE

Chemical Property:

• Melting Point: 113-115°C
• PSA: 139.90000
• LogP: -2.44904
• Storage Temp.: -20°C Freezer

Purity/Quality:

99% ^*data from raw suppliers

5-Azido-5-deoxy-D-fructose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-AZIDO-5-DEOXY-D-FRUCTOSE

There total 15 articles about 5-AZIDO-5-DEOXY-D-FRUCTOSE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

5-azido-5-deoxy-1,2-O-isopropylidene-β-D-fructopyranose (94801-01-1) → 5-azido-5-deoxy-D-fructopyranose (94801-02-2)

Guidance literature:

With Biol-Rad AG 50W-X₈ (hydrogen form); water; In ethanol; at 45 ℃; for 2h;

DOI:10.1021/jo00206a037

Reference yield: 92.0%

5-azido-5-deoxy-1,2-O-isopropylidene-β-D-fructopyranose (94801-01-1) → 5-azido-5-deoxy-D-fructopyranose (94801-02-2)

Guidance literature:

With Dowex-50W(H⁺); water; In ethanol; at 70 ℃; for 4h;

DOI:10.1021/jo00012a015

Reference yield: 81.0%

5-azido-5-deoxy-D-glucofuranose → 5-azido-5-deoxy-D-fructopyranose (94801-02-2)

Guidance literature:

With magnesium sulfate; at 60 ℃; for 3h; glucose-isomerase (EC 5.3.1.5);

DOI:10.1016/0008-6215(93)84155-Y

upstream raw materials:

5-azido-5-deoxy-1,2-O-isopropylidene-β-D-fructopyranose

5-azido-5-deoxy-1,2-O-isopropylidene-β-D-fructopyranose

1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose

3-O-benzoyl-1,2-O-isopropylidene-β-D-fructopyranose

Downstream raw materials:

2,5-dideoxy-2,5-imino-D-mannitol

(2R,3R,4R,5R)-3,4-Dihydroxy-2,5-bis-hydroxymethyl-pyrrolidine-1-carbothioic acid phenylamide

(2R,3R,4R)-2,5-Bis-hydroxymethyl-3,4-dihydro-2H-pyrrole-3,4-diol

Refernces

• 1、 Garcia-Moreno, M. Isabel,Rodriguez-Lucena, David,Ortiz Mellet, Carmen,Garcia Fernandez, Jose M.. "Pseudoamide-Type Pyrrolidine and Pyrrolizidine Glycomimetics and Their Inhibitory Activities against Glycosidases". . p. 3578 - 3581. Retrieved 2007/10/03.
• 2、 Berger, Andreas,De Raadt, Anna,Gradnig, Guenther,Grasser, Monika,Loew, Harald,Stuetz, Arnold E.. "A novel synthetic application of glucose isomerase: Quantitative conversion of D-glucose and L-idofuranose, derivatives modified at position five into the corresponding D-fructo- and L-sorbopyranoses". . p. 7125 - 7128. Retrieved 2007/10/02.