TRIS(2,4,6-TRIMETHOXYPHENYL)PHOSPHINE

Base Information

• Chemical Name: TRIS(2,4,6-TRIMETHOXYPHENYL)PHOSPHINE
• CAS No.: 91608-15-0
• Molecular Formula: C27H33 O9 P
• Molecular Weight: 532.527
• Mol file: 91608-15-0.mol

Synonyms:Tris(2,4,6-trimethoxyphenyl)phosphine

Chemical Property of TRIS(2,4,6-TRIMETHOXYPHENYL)PHOSPHINE

Chemical Property:

• Melting Point: 155-160 °C(lit.)
• Boiling Point: 645.5±55.0 °C(Predicted)
• PSA: 96.66000
• LogP: 3.52220
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Sensitive.: air sensitive
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Tris(2,4,6-trimethoxyphenyl)phosphine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Tris(2,4,6-trimethoxyphenyl)phosphine is a highly basic arylphosphine. Highly basic arylphosphine.

Technology Process of TRIS(2,4,6-TRIMETHOXYPHENYL)PHOSPHINE

There total 5 articles about TRIS(2,4,6-TRIMETHOXYPHENYL)PHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.37%

2-bromo-1,3,5-trimethoxybenzene (1131-40-4) → tris(2,4,6-trimethoxyphenyl)phosphine (91608-15-0)

Guidance literature:

2-bromo-1,3,5-trimethoxybenzene; With magnesium; In 2-methyltetrahydrofuran; at 25 - 55 ℃; for 2h;

With phosphorus trichloride; In 2-methyltetrahydrofuran; at 25 - 85 ℃; for 3h;

With hydrogenchloride; In 2-methyltetrahydrofuran; water; for 1.5h;

Reference yield: 70.0%

1-lithium-2,4,6-trimethoxybenzene (34425-71-3) → tris(2,4,6-trimethoxyphenyl)phosphine (91608-15-0)

Guidance literature:

With triphenyl phosphite; In diethyl ether; 0 deg C to r.t.;

DOI:10.1039/c39840000482

Reference yield:

1,2,3-trimethoxybenzene (621-23-8) → tris(2,4,6-trimethoxyphenyl)phosphine (91608-15-0)

Guidance literature:

With phosphorus trichloride;

upstream raw materials:

1,2,3-trimethoxybenzene

1-lithium-2,4,6-trimethoxybenzene

triphenyl phosphite

2-bromo-1,3,5-trimethoxybenzene

Downstream raw materials:

tris(2,4,6-trimethoxyphenyl)phosphine oxide

PCl(C₆H₂(OCH₃)3)3⁽¹⁺⁾*FeCl₄^(1-)={PCl(C₆H₂(OCH₃)3)3}{FeCl₄}

(C₆H₂(OCH₃)3)3PCl⁽¹⁺⁾*GeCl₃^(1-) = [(C₆H₂(OCH₃)3)3PCl]GeCl₃

bromo[tris(2,4,6-trimethoxyphenyl)phosphine]gold(I)

Refernces

• 1、 Baker, Lisa-Jane,Bott, Raymond C.,Bowmaker, Graham A.,Healy, Peter C.,Skelton, Brian W.,et al.. "Structural, Far-infrared and 31P Nuclear Magnetic Resonance Studies of Two-co-ordinate Complexes of Tris(2,4,6-trimethoxyphenyl)phosphine with Gold(I) Halides". . p. 1341 - 1348. Retrieved 2007/10/02.
• 2、 Wada, Masanori,Hidashizaki, Shogo. "A Highly Basic Triphenylphosphine, 3P". . p. 482 - 483. Retrieved 2007/10/02.