1-DEOXY-1-NITRO-D-IDITOL HEMIHYDRATE

Base Information

• Chemical Name: 1-DEOXY-1-NITRO-D-IDITOL HEMIHYDRATE
• CAS No.: 96613-89-7
• Molecular Formula: C6H13 N O7
• Molecular Weight: 211.172
• Hs Code.: 2905590090
• Mol file: 96613-89-7.mol

Synonyms:1-Deoxy-1-nitro-D-iditol;1-Deoxy-1-nitro-D-ido-hexitol; 6-Deoxy-6-nitro-D-iditol

Chemical Property of 1-DEOXY-1-NITRO-D-IDITOL HEMIHYDRATE

Chemical Property:

• Melting Point: 88 °C(lit.)
• PSA: 156.20000
• LogP: -2.84210

Purity/Quality:

99% ^*data from raw suppliers

1-Deoxy-1-nitro-D-iditol hemihydrate ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-DEOXY-1-NITRO-D-IDITOL HEMIHYDRATE

There total 2 articles about 1-DEOXY-1-NITRO-D-IDITOL HEMIHYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

D-xylose (58-86-6) + nitromethane (75-52-5) → 1-deoxy-1-nitro-D-ido-hexitol (96613-89-7) + 1-deoxy-1-nitro-D-gulo-hexitol (114612-66-7)

Guidance literature:

With sodium; In methanol; at 20 ℃; for 16h;

DOI:10.1016/S0008-6215(98)00048-2

Reference yield: 61.0%

nitromethane (75-52-5) + L-arabinose (532-20-7,613-83-2,7261-25-8,7687-39-0,13221-22-2,14795-83-6,15761-67-8,20074-49-1,25545-03-3,25545-04-4,32445-75-3,34436-17-4,36441-93-7,36468-53-8,37110-85-3,37388-49-1,38029-69-5,40461-77-6,40461-89-0,41546-19-4,41546-20-7,41546-21-8,41546-26-3,41546-29-6,41546-30-9,41546-31-0,126872-16-0,131064-98-7) → (2S,3S,4S)-6-Nitro-hexane-1,2,3,4,5-pentaol (6027-42-5,14199-83-8,14199-88-3,20971-06-6,69257-51-8,74183-68-9,94481-72-8,96613-89-7,97466-53-0,97907-36-3,105499-37-4,107080-35-3,107080-36-4,114612-65-6,114612-66-7,120019-25-2)

Guidance literature:

With sodium methylate; In methanol; for 50h;

DOI:10.1021/jo00174a028

Reference yield: 68.0%

1-deoxy-1-nitro-D-ido-hexitol (96613-89-7) → D-idose (5978-95-0)

Guidance literature:

With sodium hydroxide; sulfuric acid; In water; at 10 - 20 ℃; for 1h;

DOI:10.1016/S0008-6215(98)00048-2

upstream raw materials:

D-xylose

nitromethane

L-arabinose

Downstream raw materials:

D-idose

1,2:5,6-di-O-isopropylidene-α-L-glucofuranose

Refernces

• 1、 Dromowicz, Manfred,Koell, Peter. "A convenient synthesis of D-idose". . p. 169 - 171. Retrieved 2007/10/03.
• 2、 Grethe,Mitt,Williams,Uskokovic. "Synthesis of daunosamine". . p. 5309 - 5315. Retrieved 2007/10/02.