[2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine

Base Information

• Chemical Name: [2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine
• CAS No.: 1868-85-5
• Molecular Formula: C7H3F7N2
• Molecular Weight: 248.103
• Hs Code.: 2928000090
• European Community (EC) Number: 620-800-9
• NSC Number: 170067
• DSSTox Substance ID: DTXSID60305265
• Nikkaji Number: J1.155.296J
• Wikidata: Q82051842
• Mol file: 1868-85-5.mol

Synonyms:1868-85-5;[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine;2,3,5,6-Tetrafluoro-4-hydrazinobenzotrifluoride;Tetrafluoro-4-(trifluoromethyl)phenylhydrazine;2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl-hydrazine;2,3,5,6-TETRAFLUORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE;(Perfluoro-p-tolyl)hydrazine;MFCD00012368;(alpha,alpha,alpha,2,3,5,6-Heptafluoro-p-tolyl)hydrazine;Hydrazine, [2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-;(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)hydrazine;NSC170067;SCHEMBL7713045;DTXSID60305265;STK273600;AKOS003379350;NSC 170067;NSC-170067;AS-67353;BB 0262112;C(F)(F)(F)c1c(F)c(F)c(NN)c(F)c1F;FT-0609411;H1034;(Tetrafluoro-4-trifluoromethyl)phenylhydrazine;D90996;A813094;2,3,5,6-tetrafluoro-4-trifluoromethylphenylhydrazine;4-(Trifluoromethyl)-2,3,5,6-tetrafluorophenylhydrazine;.alpha.,.alpha.,.alpha.,2,3,5,6-Heptafluoro-p-tolylhydrazine;1-[2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine #

Chemical Property of [2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine

Chemical Property:

• Melting Point: 81-83 °C(lit.)
• Boiling Point: 142.9 °C at 760 mmHg
• PKA: 3.30±0.40(Predicted)
• Flash Point: 40.2 °C
• PSA: 38.05000
• Density: 1.694 g/cm³
• LogP: 3.32070
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 1
• Exact Mass: 248.01844524
• Heavy Atom Count: 16
• Complexity: 229

Purity/Quality:

98%,99%, ^*data from raw suppliers

[2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1(=C(C(=C(C(=C1F)F)NN)F)F)C(F)(F)F
• Uses: [2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine is used in preparing useful herbicides and plant growth regulators.

Technology Process of [2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine

There total 1 articles about [2,3,5,6-Tetrafluoro-4-(trifluoromethyl)phenyl]hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

perfluorotoluene (434-64-0) → (2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)hydrazine (1868-85-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 6h; Reflux;

DOI:10.1016/j.jfluchem.2018.06.011

Reference yield: 98.0%

2-methoxy-3,3,6,6-tetramethoxy-1,4-cyclohexadiene (74097-22-6) + (2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)hydrazine (1868-85-5) → 3',4'-dimethoxy-2,3,5,6-tetrafluoro-4-trifluoromethylazobenzene

Guidance literature:

With ammonium cerium(IV) nitrate; In acetonitrile; at 20 ℃; for 0.0833333h;

DOI:10.1021/jo0498011

Reference yield: 98.0%

(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)hydrazine (1868-85-5) + 3,3,6,6-tetramethoxy-2-(p-tolylsulfinyl)-1,4-cyclohexadiene → 4'-methoxy-3'-(p-tolylsulfinyl)-2,3,5,6-tetrafluoro-4-trifluoromethylazobenzene

Guidance literature:

With ammonium cerium(IV) nitrate; In acetonitrile; at 20 ℃; for 2h;

DOI:10.1021/jo0498011

upstream raw materials:

perfluorotoluene

Downstream raw materials:

iodo-2,3,5,6-tetrafluoro-4-trifluoromethyl-benzene

4-CF₃-C₆F₄NHNCHC₆H₅

1,2,4,5-tetrafluoro-3-(trifluoromethyl)benzene

2,3,6-trifluorobenzoic acid

Refernces