2-Fluoro-6-vinylpyridine

Base Information

• Chemical Name: 2-Fluoro-6-vinylpyridine
• CAS No.: 869108-67-8
• Molecular Formula: C₇H₆FN
• Molecular Weight: 123.13
• Hs Code.: 2933499090
• Mol file: 869108-67-8.mol

Synonyms:2-Fluoro-6-vinylpyridine

Chemical Property of 2-Fluoro-6-vinylpyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2-Fluoro-6-vinylpyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Fluoro-6-vinylpyridine

There total 1 articles about 2-Fluoro-6-vinylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-6-fluoropyridine (144100-07-2) → 2-Fluoro-6-vinylpyridine (869108-67-8)

Guidance literature:

potassium vinyltrifluoroborate; With triethylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In propan-1-ol;

2-bromo-6-fluoropyridine; In propan-1-ol; at 20 - 100 ℃; for 59h;

Reference yield:

2-Fluoro-6-vinylpyridine (869108-67-8) + 4-iodobenzoic acid ethyl ester (51934-41-9) → Ethyl 4-[(E)-2-(6-fluoropyridin-2-yl)vinyl]benzenecarboxylate (869108-68-9)

Guidance literature:

With triethylamine; palladium diacetate; triphenylphosphine; at 100 ℃; for 16h;

upstream raw materials:

2-bromo-6-fluoropyridine

Downstream raw materials:

Ethyl 4-[(E)-2-(6-fluoropyridin-2-yl)vinyl]benzenecarboxylate

Refernces