Methyl 2-aminocyclopentanecarboxylate

Base Information

• Chemical Name: Methyl 2-aminocyclopentanecarboxylate
• CAS No.: 342419-20-9
• Molecular Formula: C7H13 N O2
• Molecular Weight: 143.18362
• Hs Code.: 2922499990
• DSSTox Substance ID: DTXSID00563140
• Mol file: 342419-20-9.mol

Synonyms:Methyl 2-aminocyclopentanecarboxylate;342419-20-9;Methyl 2-aminocyclopentane-1-carboxylate;2-AMINO-CYCLOPENTANECARBOXYLIC ACID METHYL ESTER;Cyclopentanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI);SCHEMBL596961;SCHEMBL15383186;DTXSID00563140;RGXCCQQWSIEIEF-UHFFFAOYSA-N;Methyl2-aminocyclopentanecarboxylate;AKOS006339049;SB45778;CS-0451378;EN300-146440;A847716

Chemical Property of Methyl 2-aminocyclopentanecarboxylate

Chemical Property:

• PSA: 52.32000
• LogP: 0.98710
• Storage Temp.: 2-8°C
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 143.094628657
• Heavy Atom Count: 10
• Complexity: 136

Purity/Quality:

99% ^*data from raw suppliers

2-Amino-cyclopentanecarboxylicacidmethylester 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1CCCC1N

Technology Process of Methyl 2-aminocyclopentanecarboxylate

There total 1 articles about Methyl 2-aminocyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

methanol (67-56-1) + 2-aza-3-oxobicyclo<3.2.0>heptane (22031-52-3) → methyl 2-aminocyclopentanecarboxylate (342419-20-9,170421-23-5)

Guidance literature:

With SiO₂-Cl; sodium hydrogencarbonate; at 0 ℃; for 0.333333h;

DOI:10.1246/cl.2006.1004

Reference yield:

methyl 2-aminocyclopentanecarboxylate (342419-20-9,170421-23-5) + 5-Bromo-2-aminobenzoic acid (5794-88-7) → C14H17BrN2O3

Guidance literature:

With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In dichloromethane; at 0 - 20 ℃; for 16h;

upstream raw materials:

methanol

2-aza-3-oxobicyclo<3.2.0>heptane

Refernces