P-AMINOPHENYL-BETA-D-CELLOBIOSIDE

Base Information

• Chemical Name: P-AMINOPHENYL-BETA-D-CELLOBIOSIDE
• CAS No.: 42935-24-0
• Molecular Formula: C18H27 N O11
• Molecular Weight: 433.412
• Mol file: 42935-24-0.mol

Synonyms:4-Aminophenylb-D-cellobioside

Chemical Property of P-AMINOPHENYL-BETA-D-CELLOBIOSIDE

Chemical Property:

• Melting Point: 133-138oC
• PSA: 204.55000
• LogP: -3.14710
• Storage Temp.: Hygroscopic, -20?C Freezer, Under Inert Atmosphere
• Solubility.: Methanol, Water

Purity/Quality:

98% ^*data from raw suppliers

4-Aminophenyl b-D-cellobioside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of P-AMINOPHENYL-BETA-D-CELLOBIOSIDE

There total 4 articles about P-AMINOPHENYL-BETA-D-CELLOBIOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

p-nitrophenyl β-D-cellobioside (3482-57-3) → p-aminophenyl β-cellobioside (42935-24-0)

Guidance literature:

palladium on activated charcoal; In tetrahydrofuran; methanol; at 20 ℃;

DOI:10.1002/anie.200503900

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → p-aminophenyl β-cellobioside (42935-24-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 44 percent / tetrabutylammonium hydrogen sulfate, NaOH / CH₂Cl₂; H₂O / 3 h / Ambient temperature

2: 95 percent / NaOMe / methanol / Ambient temperature

3: H₂ / 10 percent Pd/C

With sodium hydroxide; hydrogen; sodium methylate; tetra(n-butyl)ammonium hydrogensulfate; palladium on activated charcoal; In methanol; dichloromethane; water;

DOI:10.1016/S0008-6215(98)00294-8

Reference yield:

Acetic acid (3R,4S,5R,6R)-3-acetoxy-6-acetoxymethyl-2-bromo-5-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester (69308-57-2) → p-aminophenyl β-cellobioside (42935-24-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 44 percent / tetrabutylammonium hydrogen sulfate, NaOH / CH₂Cl₂; H₂O / 3 h / Ambient temperature

2: 95 percent / NaOMe / methanol / Ambient temperature

3: H₂ / 10 percent Pd/C

With sodium hydroxide; hydrogen; sodium methylate; tetra(n-butyl)ammonium hydrogensulfate; palladium on activated charcoal; In methanol; dichloromethane; water;

DOI:10.1016/S0008-6215(98)00294-8

upstream raw materials:

p-nitrophenyl β-D-cellobioside

4-nitro-phenol

Acetic acid (3R,4S,5R,6R)-3-acetoxy-6-acetoxymethyl-2-bromo-5-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-4-yl ester

p-nitrophenyl 2,3,6-tri-O-acetyl-4-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside

Downstream raw materials:

4-bromoacetamidophenyl β-D-cellobioside

Refernces

• 1、 Sangseethong, Kunruedee,Penner, Michael H.. "p-Aminophenyl β-cellobioside as an affinity ligand for exo-type cellulases". . p. 245 - 250. Retrieved 2007/10/03.