Technology Process of 2-AMINO-3-IODO-PHENOL
There total 8 articles about 2-AMINO-3-IODO-PHENOL which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
at -78 - 20 ℃;
for 16h;
DOI:10.1021/jo025615o
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 98 percent / tetrahydrofuran / 48 h
2: 88 percent / CH2Cl2; triethylamine / 16 h
3: 30 percent / t-BuLi; 1,2-diiodoethane / diethyl ether; pentane / 16 h / -80 - 20 °C
4: TFA
5: TBAF
With
1,2-Diiodoethane; tetrabutyl ammonium fluoride; tert.-butyl lithium; trifluoroacetic acid;
In
tetrahydrofuran; diethyl ether; dichloromethane; triethylamine; pentane;
DOI:10.1021/jo025615o
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: t-BuLi / diethyl ether; pentane / 22 h / -25 °C
1.2: 61 percent / ICH2CH2Cl / diethyl ether; pentane / 16 h / 20 °C
2.1: BBr3 / CH2Cl2 / 16 h / -78 - 20 °C
With
tert.-butyl lithium; boron tribromide;
In
diethyl ether; dichloromethane; pentane;
DOI:10.1021/jo025615o
