5α-hydroxytriptonide

Base Information

• Chemical Name: 5α-hydroxytriptonide
• CAS No.: 571176-87-9
• Molecular Formula: C₂₀H₂₂O₇
• Molecular Weight: 374.39
• Mol file: 571176-87-9.mol

Synonyms:5α-hydroxytriptonide

Chemical Property of 5α-hydroxytriptonide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 5α-hydroxytriptonide

There total 2 articles about 5α-hydroxytriptonide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

l-triptonide (38647-11-9) → 5α-hydroxytriptonide (571176-87-9)

Guidance literature:

With selenium(IV) oxide; In 1,4-dioxane; for 24h; Reflux; Inert atmosphere;

DOI:10.1016/j.bmcl.2014.10.069

Reference yield: 5.0%

l-triptonide (38647-11-9) → triptolide (38748-32-2,73414-46-7,73543-06-3,144539-79-7) + 5α-hydroxytriptonide (571176-87-9) + 17-hydroxyl-triptonide

Guidance literature:

With Aspergillus niger (AS 3.739); In acetone; at 25 ℃; for 120h; Product distribution;

DOI:10.1055/s-2003-43220

upstream raw materials:

l-triptonide

Refernces

• 1、 Ning, Lili,Qu, Guiqin,Ye, Min,Guo, Hongzhu,Bi, Kaishun,Guo, Dean. "Cytotoxic Biotransformed Products from Triptonide by Aspergillus niger". . p. 804 - 808. Retrieved 2007/10/03.