Phenol, 2-chloro-4,6-difluoro-

Base Information

• Chemical Name: Phenol, 2-chloro-4,6-difluoro-
• CAS No.: 2267-99-4
• Molecular Formula: C₆H₃ClF₂O
• Molecular Weight: 164.539
• Hs Code.: 2908199090
• Mol file: 2267-99-4.mol

Synonyms:2-Chloro-4,6-difluorophenol

Chemical Property of Phenol, 2-chloro-4,6-difluoro-

Chemical Property:

• PSA: 20.23000
• LogP: 2.32380
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-4,6-difluorophenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenol, 2-chloro-4,6-difluoro-

There total 2 articles about Phenol, 2-chloro-4,6-difluoro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-difluorophenol (367-27-1) → 2-chloro-4,6-difluoro-phenol (2267-99-4)

Guidance literature:

With chlorine;

DOI:10.1021/ja01510a021

Reference yield:

2,4-difluorophenylamine (367-25-9,76563-56-9) → 2-chloro-4,6-difluoro-phenol (2267-99-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous sulfuric acid; sodium nitrite / Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat auf 180grad

2: chlorine

With sulfuric acid; chlorine; sodium nitrite;

DOI:10.1021/ja01510a021

Reference yield:

2-chloro-4,6-difluoro-phenol (2267-99-4) + chloroacetic acid (79-11-8) → (2-chloro-4,6-difluoro-phenoxy)-acetic acid (1979-24-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja01510a021

upstream raw materials:

2,4-difluorophenol

2,4-difluorophenylamine

Downstream raw materials:

(2-chloro-4,6-difluoro-phenoxy)-acetic acid