Diphenylphosphinodithioic acid

Base Information

• Chemical Name: Diphenylphosphinodithioic acid
• CAS No.: 1015-38-9
• Molecular Formula: C12H11 P S2
• Molecular Weight: 250.325
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID701296960
• Nikkaji Number: J103.470G
• Mol file: 1015-38-9.mol

Synonyms:Diphenylphosphinodithioic acid;1015-38-9;Diphenyldithiophosphonic acid;Diphenyldithiophosphinic acid;Phosphinodithioic acid, diphenyl-;diphenyl-sulfanyl-sulfanylidene-lambda5-phosphane;Phosphinodithioic acid, P,P-diphenyl-;Dithiodiphenylphosphinic acid;SCHEMBL454858;P,P-Diphenylphosphinodithioic acid;DTXSID701296960;BAA01538;BBL000037;MFCD00014457;STK325716;AKOS005433558;diphenyl(sulfanyl)-|E?-phosphanethione;diphenyl-sulfanyl-sulfanylidenephosphorane;diphenyl(sulfanyl)-lambda5-phosphanethione;CS-0270198;FT-0633250;EN300-92964;E77869

Chemical Property of Diphenylphosphinodithioic acid

Chemical Property:

• Vapor Pressure: 4.5E-05mmHg at 25°C
• Melting Point: 55-56°C
• Refractive Index: 1.655
• Boiling Point: 360.8°Cat760mmHg
• Flash Point: 172°C
• PSA: 80.70000
• Density: 1.25g/cm³
• LogP: 3.61230
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly)
• XLogP3: 4.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 250.00397970
• Heavy Atom Count: 15
• Complexity: 218

Purity/Quality:

98%,99%, ^*data from raw suppliers

DiphenylphosphinodithioicAcid(>90%) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=S)(C2=CC=CC=C2)S
• Uses: Diphenyldithiophosphonic acid is used in place of phenyl phosphate for acylation of nucleotides.

Technology Process of Diphenylphosphinodithioic acid

There total 14 articles about Diphenylphosphinodithioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

diphenylthiophosphinoyl chloride (1015-37-8) + sodium diphenylphosphinodithioate (5827-17-8) → diphenylphosphinodithioic acid (1015-38-9)

Guidance literature:

diphenylthiophosphinoyl chloride; With sodium hydrogensulfide; In water; at 95 ℃; for 2h;

sodium diphenylphosphinodithioate; With hydrogenchloride; In water; at 20 ℃; for 0.5h; Reagent/catalyst; Temperature; Time; Solvent;

DOI:10.1021/op300147f

Reference yield: 75.0%

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → diphenylphosphinodithioic acid (1015-38-9)

Guidance literature:

With aluminium trichloride; tetraphosphorus decasulfide;

DOI:10.1039/b201233b

Reference yield: 44.0%

diphenylthiophosphinoyl chloride (1015-37-8) → [phenyl(sulfanyl)phosphoroso]benzene (14278-72-9) + diphenylphosphinodithioic acid (1015-38-9)

Guidance literature:

diphenylthiophosphinoyl chloride; With sodium hydrogen sulfide; In water; at 95 ℃; for 1h;

With hydrogenchloride; In water;

DOI:10.1071/CH20169

upstream raw materials:

chloro-diphenylphosphine

diphenylphosphane

benzene

aluminium trichloride

Downstream raw materials:

diphenyl-dithiophosphinic acid-(1,3-dimethyl-butyl ester)

Diphenyldithiophosphinsaeure-<2,3-dihydroxy-propylester>

Diphenyl-phosphinodithioic acid 2-oxo-2-phenyl-ethyl ester

2-<α-(Diphenyl-thiophosphinylmercapto)-benzyl>-indandion-(1.3)

Refernces

• 1、 Senevirathna, Dimuthu C.,Duffin, Rebekah N.,Stephens, Liam J.,Herdman, Megan E.,Werrett, Melissa V.,Andrews, Philip C.. "Bismuth(iii) Thiophosphinates: Understanding How a Small Atomic Change Influences Antibacterial Activity and Mammalian Cell Viability". . p. 1226 - 1236. Retrieved 2020/10/07.
• 2、 Kanemura, Shigenari,Kondoh, Azusa,Yasui, Hiroto,Yorimitsu, Hideki,Oshima, Koichiro. "Regio- and stereoselective additions of diphenyldithiophosphinic acid to N-(1-alkynyl)amides and 1-alkynyl sulfides". experimental part. p. 506 - 514. Retrieved 2009/04/07.