2-Dimethylamino-7-nitrofluorene

Base Information

• Chemical Name: 2-Dimethylamino-7-nitrofluorene
• CAS No.: 19221-04-6
• Molecular Formula: C₁₅H₁₄N₂O₂
• Molecular Weight: 254.288
• Hs Code.: 2921499090
• DSSTox Substance ID: DTXSID60396072
• Nikkaji Number: J644.782A
• Wikidata: Q82196561
• Mol file: 19221-04-6.mol

Synonyms:2-DIMETHYLAMINO-7-NITROFLUORENE;19221-04-6;N,N-dimethyl-7-nitro-9H-fluoren-2-amine;9H-Fluoren-2-amine,N,N-dimethyl-7-nitro-;Oprea1_444869;DTXSID60396072;STK367260;AKOS005444040;2-(N;N,N-Dimethyl-7-nitro-9H-fluorene-2-amine;2-(N,N-dimethylamino)-7-nitro-9h-fluorene;FT-0751859

Chemical Property of 2-Dimethylamino-7-nitrofluorene

Chemical Property:

• Vapor Pressure: 6.05E-08mmHg at 25°C
• Refractive Index: 1.677
• Boiling Point: 440.1 °C at 760 mmHg
• Flash Point: 220 °C
• PSA: 49.06000
• Density: 1.283 g/cm³
• LogP: 3.75520
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 254.105527694
• Heavy Atom Count: 19
• Complexity: 353

Purity/Quality:

99% ^*data from raw suppliers

2-DIMETHYLAMINO-7-NITROFLUORENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)[N+](=O)[O-]

Technology Process of 2-Dimethylamino-7-nitrofluorene

There total 3 articles about 2-Dimethylamino-7-nitrofluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-amino-7-nitrofluorene (1214-32-0) → 2-dimethylamino-7-nitrofluorene (19221-04-6)

Guidance literature:

With sodium cyanoborohydride; acetic acid; at 25 ℃; for 24h;

DOI:10.1021/jo035204n

Reference yield: 30.0%

trimethyl phosphite (512-56-1) + 2-amino-7-nitrofluorene (1214-32-0) → 2-dimethylamino-7-nitrofluorene (19221-04-6)

Guidance literature:

30 min at 150 deg C, 160 to 170 deg C, 2 h at 150 deg C;

Reference yield:

→ 2-dimethylamino-7-nitrofluorene (19221-04-6)

Guidance literature:

upstream raw materials:

trimethyl phosphite

2-amino-7-nitrofluorene

formaldehyd

Downstream raw materials:

N,N-dimethyl-fluorene-2,7-diyldiamine

Refernces

• 1、 Catalan, Javier,Lopez, Vicenta,Perez, Pilar,Martin-Villamil, Rosa,Rodriguez, Jose-Gonzalo. "Progress Towards a Generalized Solvent Polarity Scale: The Solvatochromism of 2-(Dimethylamino)-7-nitrofluorene and Its Homomorph 2-Fluoro-7-nitrofluorene". . p. 241 - 252. Retrieved 2007/10/02.