ATRACTYLOSIDE SODIUM SALT

Base Information

• Chemical Name: ATRACTYLOSIDE SODIUM SALT
• CAS No.: 100938-11-2
• Molecular Formula: C30H46 O16 S2 . 2 Na
• Molecular Weight: 770.77
• Mol file: 100938-11-2.mol

Synonyms:1H-2,10a-Ethanophenanthrene,19-norkaur-16-en-18-oic acid deriv.

Chemical Property of ATRACTYLOSIDE SODIUM SALT

Chemical Property:

• PSA: 272.14000
• LogP: 3.14340

Purity/Quality:

98%min ^*data from raw suppliers

Atractyloside sodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 23/24/25
• Safety Statements: 36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in p ermeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. ATRACTYLOSIDE SODIUM SALT induces the release of ahyaluronidase-induced murine WW domain-containing oxidore ductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity.