HEXADECYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE

Base Information

• Chemical Name: HEXADECYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE
• CAS No.: 115414-49-8
• Molecular Formula: C₂₄H₄₇NO₆
• Molecular Weight: 445.64
• Mol file: 115414-49-8.mol

Synonyms:HEXADECYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE;Hexadecyl2-acetamido-2-deoxy-b-D-glucopyranoside;HEXADECYL 2-ACETAMIDO-2-DEOXY-SS-D-GLUCOPYRANOSIDE

Chemical Property of HEXADECYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE

Chemical Property:

• PSA: 108.25000
• LogP: 3.81890

Purity/Quality:

98% ^*data from raw suppliers

HEXADECYL-2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of HEXADECYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE

There total 3 articles about HEXADECYL 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

hexadecyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside (115414-47-6) → hexadecyl 2-acetamido-2-deoxy-β-D-glucopyranoside (115414-49-8)

Guidance literature:

With sodium methylate; In methanol; dichloromethane; for 1h;

DOI:10.1007/BF00598682

Reference yield:

1-Hexadecanol (36653-82-4,124-29-8) → hexadecyl 2-acetamido-2-deoxy-β-D-glucopyranoside (115414-49-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / p-toluenesulfonic acid / 1,2-dichloro-ethane / Heating

2: 98 percent / sodium methanolate / methanol; CH₂Cl₂ / 1 h

With sodium methylate; toluene-4-sulfonic acid; In methanol; dichloromethane; 1,2-dichloro-ethane;

DOI:10.1007/BF00598682

Reference yield:

2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline (10378-06-0,20757-53-3,35954-65-5,123483-77-2,134308-33-1) → hexadecyl 2-acetamido-2-deoxy-β-D-glucopyranoside (115414-49-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / p-toluenesulfonic acid / 1,2-dichloro-ethane / Heating

2: 98 percent / sodium methanolate / methanol; CH₂Cl₂ / 1 h

With sodium methylate; toluene-4-sulfonic acid; In methanol; dichloromethane; 1,2-dichloro-ethane;

DOI:10.1007/BF00598682

upstream raw materials:

hexadecyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside

1-Hexadecanol

2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)[1,2-d]-2-oxazoline

Downstream raw materials:

O-(hexadecyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranosid-3-yl)-D-lactoyl-L-alanyl-D-isoglutamine γ-benzyl ester

hexadecyl 2-acetamido-4,6-O-benzylidene-3-O-(D-1-carboxyethyl)-2-deoxy-β-D-glucopyranoside

hexadecyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-glucopyranoside

Refernces