Sodium trifluoromethanesulfinate

Base Information

• Chemical Name: Sodium trifluoromethanesulfinate
• CAS No.: 2926-29-6
• Molecular Formula: CF3NaO2S
• Molecular Weight: 156.061
• Hs Code.: 29309090
• Mol file: 2926-29-6.mol

Synonyms:Methanesulfinicacid, trifluoro-, sodium salt (8CI,9CI);Sodium triflinate;Sodiumtrifluoromethanesulfinate;Sodium trifluoromethylsulfinate;

Chemical Property of Sodium trifluoromethanesulfinate

Chemical Property:

• Vapor Pressure: 0.0369mmHg at 25°C
• Melting Point: <325°C
• Boiling Point: 222.8 °C at 760 mmHg
• Flash Point: 88.5 °C
• PSA: 59.34000
• LogP: 1.25100
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: Water (Sparingly)

Purity/Quality:

99% ^*data from raw suppliers

Sodium triflinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-36/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Efficient sulfinate salt for the trifluoromethylation of various aryls, aryl boronic acids, alkenes, and alkynes. Sodium Triflinate, is a sulfur-containing building block and Fluorination reagents, used in various organic synthesis. It can be used in a new and convenient method for the copper-catalyzed construction of functional sulfonamides in good yields and excellent chemoselectivity.

Technology Process of Sodium trifluoromethanesulfinate

There total 13 articles about Sodium trifluoromethanesulfinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl 3-(trifluoromethanesulfonyl)propionate (155201-03-9) → Langlois reagent (2926-29-6) + ethyl acrylate (140-88-5,9003-32-1)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃;

DOI:10.1016/j.jfluchem.2007.04.012

Reference yield: 98.0%

trifluoromethanesulfinic acid (34642-42-7) → Langlois reagent (2926-29-6)

Guidance literature:

With sodium carbonate; In ethanol; stoich. amts. of educts in dry ethanol;

DOI:10.1016/S0022-1139(00)83984-6

Reference yield: 93.0%

sodium azide + Trifluoromethanesulfonyl fluoride (335-05-7) → Langlois reagent (2926-29-6)

Guidance literature:

In methanol; passing CF3SO2F into a susp. of NaN3 in methanol at 60°C, 4 h, stirring 12 h;

upstream raw materials:

Bromotrifluoromethane

Trifluormethansulfinsaeure-Azid

chlorotrifluoromethane

[1-(trifluoromethylsulfonyl)ethane-1,2-diyl]dibenzene

Downstream raw materials:

1-phenyl-2-((trifluoromethyl)sulfonyl)ethan-1-one

2,4-difluoro-1-trifluoromethanesulfinyl-benzene

iodotrifluoromethane

5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylthio)-1H-pyrazole-3-carbonitrile

Refernces

• 1、 Xiong, Yan-Shi,Zhang, Bin,Yu, Yang,Weng, Jiang,Lu, Gui. "Construction of Sulfonyl Phthalides via Copper-Catalyzed Oxysulfonylation of 2-Vinylbenzoic Acids with Sodium Sulfinates". . p. 13465 - 13472. Retrieved 2019/10/16.
• 2、 Cao, Hai-Ping,Chen, Qing-Yun. "Practical and efficient synthesis of perfluoroalkyl iodides from perfluoroalkyl chlorides via modified sulfinatodehalogenation". . p. 1187 - 1190. Retrieved 2008/02/10.