3-Pyridinemethanamine 1-oxide

Base Information

• Chemical Name: 3-Pyridinemethanamine 1-oxide
• CAS No.: 106940-10-7
• Molecular Formula: C6H8N2O
• Molecular Weight: 124.14
• Hs Code.: 2933399090
• Mol file: 106940-10-7.mol

Synonyms:1-(1-oxidopyridin-3-yl)methanamine;3-Aminomethylpyridine-N-Oxide;C-(1-Oxy-pyridin-3-yl)-methylamine;

Chemical Property of 3-Pyridinemethanamine 1-oxide

Chemical Property:

• Vapor Pressure: 3.41E-05mmHg at 25°C
• Refractive Index: 1.567
• Boiling Point: 354.2 °C at 760 mmHg
• Flash Point: 168 °C
• PSA: 51.48000
• Density: 1.18 g/cm³
• LogP: 1.27410

Purity/Quality:

98%Min ^*data from raw suppliers

3-Aminomethylpyridine-N-oxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinemethanamine 1-oxide

There total 9 articles about 3-Pyridinemethanamine 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

3-Aminomethylpyridine (3731-52-0) → 1-(1-oxidopyridin-3-yl)methanamine (106940-10-7)

Guidance literature:

With 1,2-diphenyl-1,1,2,2-tetrahydroperoxyethane; In acetonitrile; at 20 ℃; for 0.25h;

DOI:10.1007/s13738-015-0776-8

Reference yield: 85.0%

3-<amino>methyl>pyridine N-oxide (110295-94-8) → 3-(aminomethyl)pyridine N-oxide hydrochloride (106940-10-7)

Guidance literature:

With hydrogenchloride; formic acid; for 0.166667h; Ambient temperature;

DOI:10.1021/jm00395a008

Reference yield: 80.0%

9H-fluoren-9-ylmethyl [(1-oxidopyridin-3-yl)methyl]carbamate → 1-(1-oxidopyridin-3-yl)methanamine (106940-10-7)

Guidance literature:

With triethylamine; In chloroform; for 5h; Heating;

DOI:10.1016/j.steroids.2013.10.003

upstream raw materials:

3-<amino>methyl>pyridine N-oxide

3-Aminomethylpyridine

3-<amino>methyl>pyridine

Downstream raw materials:

5-chloro-3-ethyl-N-[(1-oxido-pyridinyl)methyl]pyrazolo-[1,5-a]pyrimidine-5.7(4H,6H)-dion-7-amine

Refernces

• 1、 Bildziukevich, Uladzimir,Rárová, Lucie,?aman, David,Havlí?ek, Libor,Dra?ar, Pavel,Wimmer, Zdeněk. "Amides derived from heteroaromatic amines and selected steryl hemiesters". . p. 1347 - 1352. Retrieved 2013.
• 2、 -. "Process and intermediates for the synthesis of (3-alkyl-5-piperidin-1-yl-3,3a-dihydro-pyrazolo[1,5-a]pyrimidin-7-yl)-amino derivatives and intermediates". Page/Page column 12. . Retrieved 2008/06/13.