CID 10306088

Base Information

• Chemical Name: CID 10306088
• CAS No.: 134524-84-8
• Molecular Formula: C₄₄H₃₂Cl₂P₂Ru
• Molecular Weight: 794.662
• Hs Code.: 28439000
• European Community (EC) Number: 634-379-4
• Mol file: 134524-84-8.mol

Synonyms:134524-84-8;Dichloro [(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphathyl] ruthenium(II);[(R)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) Dichloride;[(S)-2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) Dichloride;Dichloro[(R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II);dichloro[(s)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(ii);AKOS015999591;B3067;B3068;J-400844;J-400845;(R)-[2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl]dichlororuthenium;(R)-[1,1'-Binaphthalene]-2,2'-diylbis[diphenylphosphine]ruthenium complex

Chemical Property of CID 10306088

Chemical Property:

• Melting Point: >300 °C
• Boiling Point: 724.3 °C at 760 mmHg
• Flash Point: 419 °C
• PSA: 27.18000
• LogP: 2.64900
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: air sensitive
• Solubility.: Benzene (Slightly, Heated), Dichloromethane (Slightly, Heated)
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 7
• Exact Mass: 794.039971
• Heavy Atom Count: 49
• Complexity: 797

Purity/Quality:

98%,99%, ^*data from raw suppliers

[(S)-2,2''-Bis(diphenylphosphino)-1,1''-binaphthyl]dichlororuthenium ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=C(C4=CC=CC=C4C=C3)C5=C(C=CC6=CC=CC=C65)P(C7=CC=CC=C7)C8=CC=CC=C8.[Cl-].[Cl-].[Ru+2]
• Uses: [(S)-2,2''-Bis(diphenylphosphino)-1,1''-binaphthyl]dichlororuthenium is used as a catalyst in the asymmetric synthesis of chiral δ-lactones and in the stereoselective synthesis of (hydroxy)amino acids via asymmetric hydrogenation of aminoketo esters.

Technology Process of CID 10306088

There total 5 articles about CID 10306088 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{Ru((S)-binap)(OCOCH3)2} → dichloro[(S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) (134524-84-8,115245-70-0,132071-87-5)

Guidance literature:

With hydrogenchloride; In dichloromethane; addn. of HCl-satd. CH2Cl2 to Ru-complex soln., stirring 15 min. (Ar); evapn., addn. of CH2Cl2, evapn. (repeated 3 times), drying (vac., overnight);

DOI:10.1002/hlca.19920750811

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + (R)-(+)-2,2’-bis(diphenylphosphino)-1,1’-binaphthalene (76189-55-4,76189-56-5,98327-87-8) + (cycloocta-1,5-diene)Ru(2-methylallyl)2 (12289-94-0,1263002-58-9) → (R)-BINAP-RuCl2 (134524-84-8,115245-70-0,132071-87-5)

Guidance literature:

In acetone; solvent removed in vac.;

DOI:10.1016/j.molcata.2009.06.024

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + [bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II) + (R)-(+)-2,2’-bis(diphenylphosphino)-1,1’-binaphthalene (76189-55-4,76189-56-5,98327-87-8) → (R)-BINAP-RuCl2 (134524-84-8,115245-70-0,132071-87-5)

Guidance literature:

In methanol; acetone; Ru-complex, ligand were dissolved in acetone, HCl in MeOH was added, stirred for 1 h; solvent was removed in vacuo;

DOI:10.1002/1522-2675(200202)85:2<633::AID-HLCA633>3.0.CO;2-1

upstream raw materials:

hydrogenchloride

(R)-(+)-2,2’-bis(diphenylphosphino)-1,1’-binaphthalene

(cycloocta-1,5-diene)Ru(2-methylallyl)2

Refernces

• 1、 Starodubtseva,Turova,Vinogradov,Gorshkova,Ferapontov. "Enantioselective hydrogenation of levulinic acid esters in the presence of the RuII-BINAP-HCl catalytic system". . p. 2374 - 2378. Retrieved 2007/10/03.
• 2、 Cesarotti, Edoardo,Antognazza, Patrizia,Mauri, Angela,Pallavicini, Marco,Villa, Luigi. "Ruthenium-Catalyzed Enantioselective Hydrogenation of 1,3-O-Disubstituted 1,3-Dihydroxypropan-2-ones". . p. 2563 - 2571. Retrieved 2007/10/02.