2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide

Base Information

• Chemical Name: 2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide
• CAS No.: 106966-25-0
• Molecular Formula: C7H17N2O2.Br
• Molecular Weight: 110.16
• European Community (EC) Number: 682-348-9
• UNII: 7U369DR9PL
• DSSTox Substance ID: DTXSID00546498
• Mol file: 106966-25-0.mol

Synonyms:106966-25-0;2-(3-METHOXY-3-OXOPROPYL)-1,1,1-TRIMETHYLHYDRAZINIUM BROMIDE;Propanoic acid, 3-(2,2,2-trimethylhydrazinyl)-, methyl ester bromide;[(3-methoxy-3-oxopropyl)amino]-trimethylazanium;bromide;XOTJZTAARPYKNA-UHFFFAOYSA-M;Meldonium impurity C;Hydrazinium, 2-(3-methoxy-3-oxopropyl)-1,1,1-trimethyl-, bromide (1:1);7U369DR9PL;3-(2,2,2-Trimethylhydrazinyl)methyl Propionate Bromide;DTXSID00546498;AKOS000425125;NS00078609;EN300-299763;Q-200326;F2173-0056;Z2732493299;BROMIDE SALT OF MELDONIUM IMPURITY C [EP IMPURITY];2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazin-1-ium bromide;2-(3-METHOXY-3-OXOPROPYL)-1,1,1-TRIMETHYLHYDRAZINIUMBROMIDE;Hydrazinium, 2-(3-methoxy-3-oxopropyl)-1,1,1-trimethyl-, bromide;2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide (1:1)

Chemical Property of 2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide

Chemical Property:

• Vapor Pressure: 5hPa at 20-25℃
• PSA: 38.33000
• Density: 1.38 at 20℃
• LogP: -2.84480
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 240.04734
• Heavy Atom Count: 12
• Complexity: 129

Purity/Quality:

99% ^*data from raw suppliers

3-(2,2,2-TRIMETHYLHYDRAZINYL)-PROPANOIC ACID METHYL ESTER BROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+](C)(C)NCCC(=O)OC.[Br-]
• Uses: 3-(2,2,2-Trimethylhydrazine)methylpropionate bromide can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Technology Process of 2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide

There total 1 articles about 2-(3-Methoxy-3-oxopropyl)-1,1,1-trimethylhydrazinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.3%

methyl bromide (74-83-9) + 1,1-dimethyl-2-(2-methoxycarbonylethyl)hydrazine (4753-43-9) → 3-(2,2,2-trimethylhydrazinium)propionic acid methyl ester bromide (106966-25-0)

Guidance literature:

In ethanol; at 0 ℃; for 1.5h;

Reference yield:

3-(2,2,2-trimethylhydrazinium)propionic acid methyl ester bromide (106966-25-0) → meldonium (76144-81-5)

Guidance literature:

3-(2,2,2-trimethylhydrazinium)propionic acid methyl ester bromide; With potassium hydroxide; ethanol; at 18 - 20 ℃; for 0.0833333 - 0.166667h;

With carbon dioxide; at 2 - 4 ℃; pH=8.1 - 8.5; Product distribution / selectivity;

upstream raw materials:

methyl bromide

1,1-dimethyl-2-(2-methoxycarbonylethyl)hydrazine

Downstream raw materials:

meldonium

Refernces